Epidemiological study on the fatty acids composition of red blood cell membrane and subclinical atherosclerosis in middle aged Japanese

为了阐明n-3脂肪酸的抗动脉粥样硬化作用，我们调查了一个社区260名中年男性亚动脉粥样硬化与红细胞膜脂肪酸的关系。红细胞膜中n-3脂肪酸的标准差小于血清中n-3脂肪酸的标准差，提示红细胞膜中n-3脂肪酸状态稳定。在日本中年男性中，红细胞膜n-3脂肪酸与冠状动脉钙化无关。

To clarify the anti-atherosclerotic effect of n-3 fatty acids, we investigated the relationship between sub-atherosclerosis and RBC membranous fatty acids in 260 middle-aged men living in a community. The standard deviation of n-3 fatty acids was smaller in RBC membrane than in serum, which suggested that RBC membranous fatty acids reflected stable condition. Among middle aged Japanese men, the n-3 fatty acids of RBC membrane was not related to coronary artery calcification.