DNA Nanoshuttles: A New Class of DNA-Binding Molecules

分子与DNA（控制遗传信息的分子）的相互作用是药物设计、疾病诊断和环境的基础。DNA纳米穿梭机是一种环状分子，它可以缠绕在DNA上，从一端穿梭到另一端。这种穿线相互作用是前所未有的，因此DNA-纳米穿梭机在涉及DNA相互作用的所有医学、生物技术和纳米技术领域都有重要的潜在应用。这项研究可能会导致新的诊断和应用程序的设计，这将有利于澳大利亚社会，并将为研究人员提供在生物技术和制药领域就业所需的技能的优秀培训。

The interaction of molecules with DNA, the molecule that controls genetic information, is fundamental to drug design, diagnosis of disease and the environment. DNA-nanoshuttles are ring-shaped molecules that thread onto DNA and shuttle from one end to the other. This threading interaction is without precedent and hence DNA-nanoshuttles have significant potential applications in all areas of medicine, biotechnology and nanotechnology that involve DNA interactions. This research may lead to the design of new diagnostics and applications that will benefit the Australian community, and will provide excellent training of researchers in skills required for employment in the biotechnology and pharmaceutical fields.