Do depolarizing currents in the endothelium evoke contraction of vascular smooth muscle?

建立我们的概念，包括一个新的收缩影响血管将有两个主要的好处。首先，它将使澳大利亚的研究保持在血管研究的领先地位，从而保持澳大利亚科学的高度国际形象。 其次，我们的概念代表了一个全新的治疗领域，用于治疗一系列涉及血管过度收缩的血管疾病。澳大利亚的药物开发和制造将有助于国民经济，药物消费可改善血管疾病患者的生活质量，这些血管疾病可能包括先兆子痫、糖尿病和高血压，这些疾病可通过药物治疗。

Establishment of our concept involving a novel constricting influence in blood vessels will have two major benefits. First, it will keep Australian research at the leading edge in blood vessel research and thus maintain a very high international profile for Australian science. Second, our concept represents a whole new field of therapeutic potential for treating a range of vascular diseases involving excessive constriction of blood vessels. The development and manufacture of drugs in Australia would contribute to the national economy, and their consumption could improve the quality of life for those suffering from vascular diseases amenable to treatment by such drugs, likely to include pre-eclampsia, diabetes, hypertension.