Development of chemosensors based on molecular spin-crossover metal complexes

在这个项目中，将开发独特的磷酸盐和氟化物响应化学传感器。特殊的受体基团将被引入到分子自旋交叉铁（II）络合物中，以允许在室温下对溶液中的自旋状态进行化学控制。在阴离子存在下自旋状态的变化将导致所需的比色和磁响应。将评价化学传感器的功能性、灵敏度和选择性。这些系统作为可切换（智能）MRI造影剂的潜力将被检查。

In this project, unique phosphates and fluoride responsive chemosensors will be developed. Special receptor groups will be introduced into molecular spin-crossover iron(II) complexes to allow chemical control of the spin state in solution at room temperature. The change of the spin state in the presence of anions will lead to the desired colorimetric and magnetic response. The functionality, sensitivity, and selectivity of chemosensors will be evaluated. The potential of these systems to act as switchable (intelligent) MRI contrast agents will be examined.