Oral Microbial Flora in Institutionalized Elderly People

这些研究不仅旨在阐明口腔疾病的发病机制，获得口腔保健的基础数据，而且揭示口腔清洁方法与口腔疾病、吞咽困难和感染性疾病之间的关系。对念珠菌、葡萄球菌、耐甲氧西林金黄色葡萄球菌等条件致病菌，变形链球菌、乳杆菌等致龋性致病菌，引起牙周炎的致病菌，口腔微生物区系与唾液量、缓冲容量、唾液生化行为、义齿设计和材料、牙数的关系进行了调查。在本研究范围内，得出以下结论：1.由于一般情况和ADL的降低，口腔中念珠菌的数量有增加的趋势。假丝酵母菌数量与乳杆菌数量呈正相关。糖尿病患者空腹血糖控制后唾液缓冲能力及唾液中乳杆菌和变形链球菌数较空腹血糖控制前明显改善。对住院老年人进行口腔清洁指导后，唾液量增加，唾液缓冲能力提高，细菌定植数量减少，CH3SH平均含量降低。舌刷的使用有利于改善依赖老年人的口腔卫生。

The studies aimed not only to determine the explication for the mechanism causing oral disease and to obtain the basic data for oral health care, but to reveal the relationship between the method of oral cleaning, oral disease, dysphagia and infectious disease. Opportunistic pathogens such as Candida, staphylococci and MRSA, pathogenic causing dental caries such as mutans streptococci and lactobacilli, pathogenic causing periodontitis, relationship between oral microbial flora and quantity of saliva, buffer capacity, biochemical behavior of saliva, design and material of denture, and number of teeth were investigated.Within the limits of this study, the following conclusions were drawn :1. Owing to reduction of general condition and ADL, a tendency of increase in the number of Candida in the oral cavity was recognized.2. Positive correlation between the number of Candida and lactobacilli was confirmed.3. After FBS control, the salivary buffering capacity and the number of lactobacilli and mutans streptococci in saliva were significantly improved from the pre-FBS control in diabetes mellitus patients.4. After the instruction for oral cleaning to institutionalized elderly, increase in the quantity of saliva, improvement on the salivary buffering capacity, reduction of the number of microbial colonization and decrease of the mean amount of CH_3SH were recognized.5. The use of a tongue brush was beneficial for the improvement of oral hygiene on the dependent elderly.