Investigation for the development of the method of evaluating regional lung function in the upright position using vertically opened MR system.

为了确定坐位和仰位时横隔膜运动的姿势差异，对10名健康男性进行了检查，采用0.5T垂直开放式磁共振系统、原装坐椅装置和特殊的表面线圈。在2~5个呼吸周期中，共获得了40个坐位和仰卧位的MR序列图像。横隔膜偏移(D.E.)在6个矢状面的3个横隔点上对两个位置进行测量。并测定了横隔膜前后部的差值。在18分中的16分，仰卧位的DEE明显大于坐位。在6个矢状位中，有5个仰卧位的前后位DE差值明显大于坐位，肺癌患者术前仰卧位的DE明显大于坐位(P<0.0 5)。术后6个点中的5个点(仰卧位)和4个点(坐位点)术后肺的D.E.均明显小于术前状态(P<0.05)。在膈神经麻痹患者中，坐位6个点中有5个点的运动诱发电位明显大于坐位(p&lt；0.5)。此外，肺气肿患者卧位和坐位时的横隔膜运动均有不同程度的降低，坐位MR成像可提供各种疾病引起的横隔膜运动异常的机制方面的补充信息。

To determine the postural difference of diaphragmatic motion between the sitting and supine position, ten healthy men were examined using a vertically open 0.5-T MR system and an original sitting chair device and a special surface coil. Forty sequential MR images were obtained both in the sitting and supine positions during 2-5 respiratory cycles. The diaphragmatic excursions (D.E.) were measured on 3 diaphragmatic points of 6 sagittal planes for both positions. The difference of D.E.between the anterior and posterior parts of the diaphragm were also determined. D.E.in the supine position was significantly greater than that in the sitting position at 16 of the 18 points. In 5 of the 6 sagittal planes, the difference of DE between posterior and anterior points was significantly larger in the supine position than in the sitting position.In the preoperative lung cancer patients, D.E.in the supine position was significantly (p<0.5) greater than in the sitting position at 10 of the 12 points. D.E.in the postoperative lung was significantly (p<0.5) smaller than that in the pre-operative state at 5 of the 6 points(supine) and at 4 of the 6 points(sitting). In the patients with phrenic nerve paralysis, D.E.was significantly greater(p<0.5) in the sitting position at 5 of the 6 points. In addition, the decrease of diaphragmatic motion in patients with pulmonary emphysema was also demonstrated in both supine and sitting positions.MR imaging in the sitting position may provide the additional information about the mechanism of abnormal diaphragmatic motion caused by various diseases.