Development of the electricity stimulation drugs discharge chip, and its practical application to the discharge control that combined lbiosensor

本研究将电刺激药物放电芯片的研制与生物传感器相结合，对放电控制进行了研究。它是将阳离子天然药物固定在基座上，利用静电的相互作用，通过表面铸件将药物放电的元件与基座电极上覆盖的Nafion电极直接反应而产生的。另一方面，间接电反应类型的元件确实产生取代联吡啶盐的吡咯衍生物，所述联吡啶盐打开放电药物对离子，并且能够通过电化学聚合反应向上固定基础来产生。通过控制控制电位电解，即使在产生这些元素的任何一个元素中，也可以控制能够控制释放的药物的排出量。另一方面，能够控制的固定药物的排出量重新…更重要的是，通过控制电流电解中的设置电位来实现。其次，对电刺激药物放电芯片与生物传感器的一体化进行了研究。当胰岛素到达治疗区域时，胰岛素从药物释放元件中排出，因为我在对靶进行监测的同时尝试了胰岛素的释放控制，即糖尿病治疗药物，首先通过药物释放元件和葡萄糖传感器。同时，使储藏室呈金字塔状，使得药物输送利用微注射等技术，通过使用硅靶，开发出一种时间周期长、能精确填充少量的可能元素，并覆盖在金膜的表面，以防止氧和氯离子等的腐蚀。并用二氧化硅薄膜翻转，以防止腐蚀甚至正负极。将电刺激放电的功能材料固定在该元件的正极上，考察了其在活体内的腐蚀性。这种电刺激药物释放芯片看到了药物输送的智慧和长时间周期，结果在溶解类似生物体的成分时完全没有受到腐蚀的影响，并得到了。较少

This research did the research regarding the discharge control that combined the development and biosensor of the electricity stimulation drugs discharge chip. It was able to produce it by fixating the cation nature drugs on the foundation by utilizing the interaction of static electricity by surface castings after the element that can discharge the drugs by a direct reaction with the electrode covered Nafion on the foundation electrode. On the other hand, an indirect electricity reaction style element does production the pyrrole derivative that replaced the bipyridinium salt that turns on the discharge drugs pair ion and able to produce by fixating upward a foundation by an electrochemical polymerization reaction. By controlling the controlled potential electrolysis, even in either element that was produced these the discharge quantity of the drugs that is fixed able to be controlled release. On the other hand, the discharge quantity of the drugs that is fixed able to be controlled re … More lease, by controlling a/the setting potential in the controlled current electrolysis. Furthermore, by making a/the setting current minimum it came the discharge start of the drugs that is fixed with a delay.Next, I did the research regarding the unification between the electricity stimulation drugs discharge chip and biosensor. The insulin was discharged from the drugs discharge element when it reached the treatment area, as I tried the discharge control of the insulin that is diabetes treatment medicine while giving monitoring to the target when it combines, passes the drugs discharge element and glucose sensor first of all. Also, make the storeroom the pyramid state such that the drugs delivery utilize the technology of microinjection etc.to the foundation by using, silicon aiming at, the development of a possible element with the long time cycle and able to fill up little quantity precisely and cover the surface in the gold membrane where can prevent the corrosion by oxygen and chlorine ion etc.and overturned with silicon dioxy film to also prevent corrosion even positive pole and, the negative pole. The drugs fixate the functionability material that discharging by electricity stimulation on the positive pole of this element, the corrosiveness inside the living body was investigated. This electricity stimulation drugs discharge chip see the wisdom which the drugs delivery are possible with the long time cycle, without being corroded without receiving the influence at all during the solution of the component similar to living body inside as a result, and obtained. Less