A study of sentinellymph nodes for malignant tumor of Head and Neck

前哨淋巴结(SLN)是已知的第一个或多个引流原发部位恶性肿瘤的结节。近年来，对早期恶性黑色素瘤(MM)患者经常进行SLN的活检。本文报告了近两年来我们发现和检查的7例多发性骨髓瘤。用蓝色染料、淋巴显像和伽马探针技术定位SLN，除了两例我们单独用蓝色染料识别SLN外。通过组织病理学分析和RT-PCR方法检测切除的SLN中是否存在转移。两种检查均发现SLN中有2例存在微转移。我们对这两个案例进行了详细的描述。在我们的七个病例中，两次检查没有发现不同的结果。我们认为，对日本早期MM患者进行SLN的识别和检查具有重要意义。此外，原发灶至区域淋巴结的淋巴管距离较短，在头颈部恶性肿瘤中，存在着难以在原发灶中发现前哨淋巴结的手工技术问题，并出现了许多接近它的图像。在检查了RI胶体直径后，我认为99mTc-植酸盐是最合适的。此外，在剂量，注射成像的时间，我检查了一种成像方法。

The sentinel lymph node (SLN) is known as the first node or nodes to drain the primary site a malignant neoplasm. Recently, the biopsy of SLN has often been performed for patients with early stages of malignant melanoma (MM). In this paper, seven cases of MM that we have identified and examined SLN during current two years are shown. SLN was localized with the techniques of blue dye, lymphoscintigraphy, and a gamma probe, except for two cases we identified SLN with blue dye alone. The presence of metastases in excised SLN was examined by the histopathologic analysis and RT-PCR procedure. Micrometastases in SLN were detected in two out of seven cases by both examinations. We describe these two cases in detail. No different result between both examinations was found in our seven cases. We believe that it should be significant to identify and examine SLN of Japanese patients with early stages of MM. In addition, distance of lymphatic vessel from primary lesion to regional lymph node was short, and, in a head and neck malignant tumor, there was a problem of a manual skill that a sentinel lymph node was hard to be detected in a primary lesion and case a lot of images that approached it. As a result of having examined RI colloid diameter, I understood that 99mTc-phytate was most suitable. Furthermore, in the dose, time to injection - imaging, I examined an imaging method.