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Does general anesthesia really control a stress into the operation? -From observation by two autonomic nerves monitors-

Does general anesthesia really control a stress into the operation? -From observation by two autonomic nerves monitors-
全身麻醉真的能控制手术压力吗?
批准号:
15592138
负责人:
UDA Akio
金额:
$1.86万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2003
资助国家:
日本
项目状态:
已结题
起止时间:
2003 至 2004

项目摘要

项目成果

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中文摘要
翻译
自主神经系统的稳定性是需要全身麻醉的因素之一。一方面,有一系列流程,称为预用药,麻醉引入(插管),麻醉维持,肌肉放松逆转(觉醒和拔管)。每个阶段使用的药物对稳定患者的ANS有多大贡献,或使用ANS监测仪进行评估。预用药的影响:预用药的咪达唑仑或hidoroxyzine不能控制鼻腔治疗的刺激。此后鼻部治疗应在麻醉引入后进行。观察本次使用的所有麻醉引入药物对麻醉维持药物的影响。挥发性麻醉药七氟醚、异氟醚和静脉麻醉药异丙酚显著,硫喷妥钠呈弱趋势。麻醉引入药不能抑制插管对交感神经系统的刺激。但由于引入时使用芬太尼刺激副交感神经系统(PSNP),呈现出维持全身ANS平衡的趋势,麻醉引入时使用芬太尼是有用的。七氟醚和异氟醚在操作过程中具有足够的ANS控制效果,且程度依赖于密度。在氧化亚氮的作用下,0.66MAC的镇痛作用有助于ANS的稳定,并且可以观察到挥发性麻醉品在MAC中的加性作用。通过硫酸阿托罗品治疗,可以接受高频成分(PSNP)的持续降低和低频成分/高频成分(ANS平衡)的短暂上升。所有病例均可接受依地芬铵联合新斯的明降低心跳率。新斯的明早期就出现了脑洞。
英文摘要
The stability of autonomic nervous system(ANS) is in one of the elements which need general anesthesia. On the one hand, there are a series of flows called premedication, anesthesia introduction (intubation), anesthesia maintenance, muscle relaxation reverse (awakening and extubation). The medicine used for every stage of the had contributed to the stabilization of a patients ANS how much, or it evaluated using of the ANS monitor.1.Influence of premedicationMidazolam or hidoroxyzine of premedication could not control the stimulus of nasal treatment. Thereafter nasal treatment should do after anesthesia introduction.2.Influence of introduction medicine and anesthesia maintenance medicineControl of ANS was observed with all anesthesia introduction medicines used this time. With sevoflurane and isofluran of volatile anesthetic drug and propofol of intravenous anesthetic, it was remarkable and with thiopental it is the weak tendency. The anesthesia introduction medicine could not hold down the stimulus to the sympathetic nervous system(SNS) by the intubation. But, with fentanyl when introducing is used, stimulating parasympathetic nerve system (PSNP), it showed the tendency where ANS balance of the whole is maintained, fentanyl at the time of anesthesia introduction was useful. Sevoflurane and isofluran have the control effect of sufficient ANS during the operation and the degree was relying on density. With nitrous oxide the analgesic action of 0.66MAC has contributed to the stability of ANS. In addition, the additive effect in MAC of the volatile narcotic was able to observed.3.ReverseBy atoropine sulfate medication, continuation of reduction of high frequency component (PSNP) and a transient rise of a low frequency component/high frequency component (balance of ANS) were accepted. Reduction in cardiac beats rate was accepted with all cases by edrophonium and neostigmine. And the edrophonium appeared at an early stage from neostigmine.
期刊论文(4)
专著(0)
科研奖励(0)
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DOI: --
发表时间: 2005
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影响因子: --
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DOI: --
发表时间: 2004
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影响因子: --
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DOI: --
发表时间: 2005
期刊: Journal of the Japanese Association for Dental Science 24
影响因子: --
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通讯作者: Uda
海外基金