C-type lectins and innate immunity in barramundi

该项目的目的是确定甘露聚糖结合凝集素（MBL），先天免疫的关键组成部分，在肺鱼和开发MBL的定量测定。该项目进一步旨在研究MBL在海豚链球菌感染过程中的作用，海豚链球菌在肺鱼和人类中引起疾病。定量分析将与更传统的分析结合使用，以评估补充饲料对肺鱼先天免疫系统的影响及其在应激期间的抗病能力。该项目将增加我们对这种鱼类先天免疫途径的理解，并有助于改进饲养策略的发展。

The project aims to identify mannan binding lectins (MBL), key components of innate immunity, in barramundi and to develop quantitative assays for MBL. The project further aims to investigate the role of MBL in infectious processes of Streptococcus iniae, which causes disease in barramundi and humans. Quantitative assays will be used in conjunction with more traditional assays to evaluate the effect of supplemented feeds on the innate immune system of barramundi and their disease resistance during times of stress. This project will increase our understanding of innate immune pathways in this fish species and aid development of improved feeding strategies.