The establishment of the functional bowel disorders treatment based on the pathophysiological study

测定4例正常对照组、3例慢性便秘患者的乙状结肠和直肠压力活动。我们使用了一个包含三个应变计压力传感器的柔性探头(31-30：柯尼斯堡仪器)。Inc.)位于距肛门2 cm、12 cm和27 cm处。探头连接在便携式便携式监护仪上(GMMS-300：STAR MEDICAL。Inc.)分析每小时收缩波的数目，并将收缩波归类为编码的I-IV型波，正常组与慢性便秘患者相比，收缩波数目较多，餐后2~4h的收缩波数目增多。并承认I、II、IV型波数增多，慢性便秘患者较正常人压力活动减少。不承认餐后2-4小时波数增加，也不承认t-…增加更多的是I-IV型波，认为在正常情况下，它变得更加速，并伴随着进食时的主动收缩波。在慢性便秘中，一般认为胃绞痛反射是通过进食引起的。但由于目前病例的数量很少，所以进一步的病例积累似乎是有必要的。用便携式袖珍监护仪从肛门测量乙状结肠和直肠约7小时的压力的方式，可以记录患者在良好的生活质量和更自然的条件下的负荷。认为这种方法作为检查功能性肠病的病理生理的方法是重要的。未来如果再加上24小时的测量，详细分析传播压力波，结合其他结直肠检查、直肠活检的回顾，认为对功能性肠病的更准确的治疗是有可能的。较少

We measured the pressure activity of sigmoid colon and rectum to the normal control 4 cases, the chronic constipation 3 cases. We used a flexible probe containing three straingauge pressure transducers (P31-30 : KONIGSBERG INSTRUMENTS. INC.) that were located 2,12 and 27cm from the anus. The probe was attached to a portable pocket monitor (GMMS-300 : STAR MEDICAL.. INC.) and pressure activity recorded.The number of the contraction waves for every one hour was analyzed, and moreover we classified the contraction waves into I-IV type waves of Code.In the normal cases there were many numbers of the waves compared with the chronic constipation patients and the number of the waves in 2-4 hours after meal increased. Moreover, it admitted the increase number of the wave of the I, II, IV.type.Chronic constipation patients showed less pressure activity than the normal cases. It didn't admit the increase of the number of the waves of 2-4 hours after meal and it admitted the increase of neither t … More he I-IV type waves.It thought that it became more accelerate which is accompanied by the active contraction wave by the meal in the normal cases. In the chronic constipation, the fact that a gastrocolic-reflex by the meal is done in the fault was suggested.But the accumulation of further case seems to be necessary, because there are currently few numbers of the cases.The way of measuring pressure in the sigmoid colon and rectum for about 7 hours from the anus using the portable pocket monitor, could record the load of the patient in the good quality of life, and the more natural condition.It thought that this way was important as the way of examining the pathophysiological of the functional bowel disorder.In the future, if adding 24hr measurements, the detailed analysis of the propagating pressure waves, the reviewing which combines the other colorectal examination, the reviewing of a rectum biopsy, it thought that it is possible development of the more accurate treatment of the functional bowel disorder. Less