A depth analysis of pathological prosses in the visual pathway using optic nervehead components in multifocal electroretinogram

利用视神经头成分的多焦视网膜电图，对视神经通路的病理过程进行了深入分析。在多焦点视觉输入系统中开发并建立了实时注视监测系统，以便在记录过程中放松患者，更好地注视。它还可以记录被测眼睛的注视图像。采用一种由37个六边形组成的刺激几何形状记录多焦视网膜电图，该刺激几何形状在临床上是可行的。我们提取了150多例视神经头成分（onhc），并对每个病例的其他临床特征进行了比较。视神经萎缩眼的ONHCs严重减少，视神经束损伤患者的对侧视网膜鼻半部分和同侧视网膜外侧半部分ONHCs减少。然而，在许多情况下，onhc的减少比静态视野的视觉缺陷更不敏感。onhc提取工艺的优化还需进一步研究。

Using optic nerve head components in multifocal electroretinogram, a depth analysis of pathological processes in the visual pathway was tried. Real-time fixation monitoring system was developed and built in the multifocal visual in-put system in order to relax the patient and facilitate the better fixation during the recordings. It also enabled the recording the fixation images of the tested eye. A stimulus geometry consisting of 37 stimulus hexagons, which is practical to be completed in clinic was applied to record multifocal electroretinogram.More than 150 cases contributed to this project Optic nerve head components (ONHCs) were extracted and compared to other clinical features in each case. ONHCs were severely reduced in eyes with optic atrophy and attenuated in nasal half of contralateral retina and in lateral half of ipsilateral retina in the patient with optic tract injury. However, in many cases ONHCs reduction was less sensitive than visual defects in static perimetry. Further researches are needed for optimization of ONHCs extraction.