Improvement of athletic performances by mild hyperthermic training which included mild hyperthermia in sports training protocol.

众所周知，热应激可诱导细胞中的热休克蛋白(HSP70)。热休克蛋白70具有修复应激损伤细胞蛋白质结构和防御多种应激反应的功能。我们报道了MH诱导的HSP70对水浸应激性溃疡、内毒素休克、肾缺血再灌流所致肾功能衰竭等实验动物的保护作用。这种MH预热保护了腿部肌肉的疲劳(科学研究助学金(C))。这些结果表明，MH将提高许多运动项目的成绩，并为体育界做出贡献。我们建议将MH总结在体育训练中的轻度高温训练(MHT)。为证实本研究的目的，将10名摔跤运动员随机分为雾化桑拿和远红外线设备加热组和对照组，分别于训练前(Test1)和训练后2d(Test2)进行运动成绩检测和HSP70、乳酸、NK活性测定。MHT可抑制Test2后乳酸的产生，提高运动成绩、HSP70和NK活性，并对肌肉疼痛有保护作用。对5名健康男性进行了肌肉疼痛检查(俯卧撑100次，下蹲100次)，有无MH)。肌肉酸痛评分、肌肉坚固度、CPK活性(肌肉炎症)和乳酸水平均显著降低。冬奥会摔跤和越野运动员证实了MH对运动成绩的改善。面向21世纪，我们推荐MHT作为HSP70的科学训练使用指标。我们可以通过MH享受任何运动，而不会肌肉疼痛。我们应该在世界范围内推广轻度高热疗法(MH)和热休克蛋白70。

It is well known that heat stress induces heat shock proteins (HSP 70) in cells. Also, mild hyperthermia (MH) induces HSP 70 that has a function as repairing the structure of proteins in stress-damaged cells and defense of cells against many kinds of stresses. We had reported the body protective effects of HSP 70 induced by MH as preconditioning using experimental animals, such as stress ulcer by water immersion, endotoxine shock, and kidney failure by reperfusion after renal-ischemia. This pre-heating by MH protected fatigue of leg muscle (Grant-in Aid for Scientific Research (C)). These results revealed that MH would improve performance of many sports and contribute for the sports world.We propose mild hyperthermic training (MHT) which concluding MH in physical training. To confirm the our purpose, ten wrestling players were divided in two groups, MTH (mist sauna and far infrared ray device heating) and control group (just training) and they were examined the levels of athletic performances and measured HSP 70, lactic acid, NK activity at before (Test1) and 2 days after MHT (Test2). MHT inhibited the production of lactic acid after Test2 and increased the athletic performances, HSP 70 and NK-activity.MH also protected muscle pain. Five healthy men were examined with muscle pain-examination (push-up ; 100times, squat ; 100times) with or without MH). Muscle pain score, muscle, solidity, CPK activity (inflammation of muscle), and Lactic acid were significantly decreased by MH.Improvement of athletic performance by MH was confirmed by wrestling and cross-country players in winter Olympic. For the 21th century, we recommended MHT as a scientific training-using index of HSP 70. We can enjoy any sports ourselves by MH without muscle pain. We should extend mild hyperthermia (MH) and HSP 70 on the world.