Cranioplasty using an internal absorbable distraction device
Cranioplasty using an internal absorbable distraction device
批准号:
16591798
负责人:
KOMURO Yuzo
金额:
$2.24万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2004
资助国家:
日本
项目状态:
已结题
起止时间:
2004 至 2006
中文摘要
多年来,颅成形术使用牵张成骨已用于颅缝闭塞患者。目前这种技术的一个缺点是需要进行第二次手术来移除设备。为了在不进行第二次手术的情况下进行这项技术,我们在兔身上使用可吸收的牵张装置进行了颅前移。在顶骨区行截骨术,在顶骨区放置可吸收牵张装置。以聚乳酸为原料制备了一种可吸收的牵引装置。术后5天开始撑开。牵张宽度为每天0.5mm。继续撑开,直到总宽度达到10mm。用x线片评价牵张的效果。颅骨成功转移。聚乳酸是一种用于骨固定植入物的可生物降解材料。内吸式牵引装置的主要缺点是与金属部件相比强度较低。在我们的实验中,证明了一种适合于颅骨牵引的可吸收装置。
英文摘要
For years, cranoiplasty using distraction osteogenesis has been used for patients with craniosynostosis. One of the current disadvantage of this technique is the necessity of a second operation to remove devices. For the purpose of performing this technique without a second operation, we performed cranial advancement by distraction using an absorbable distraction device in rabbits.Osteotomy was performed in the parietal region and an absorbable distraction device was placed in the parietal region. An absorbable distraction device was manufactured from polylactic acid. Distraction was initiated 5 days postoperatively. The width of distraction was 0.5mm per day. Distraction was continued until the total width was up to 10mm. The effect of distraction was assessed on roentgen-film.Cranial bone was successfully distracted.Polylactic acid is a biodegradable material used for bone fixation implants. The main disadvantage of an internal absorbable distraction device is its lower intensity compared with metallic components. In our experiments, it has been proven that an absorbable device is fit for the distraction of cranial bone.
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