Effects of relax dental clinic with healing music on the central nervous system, autonomic nervous system, and cardiovascular system

自2002年以来，我们在我院的放松牙科诊所为牙科恐惧症患者进行牙科治疗。本研究的目的是探讨治疗音乐和笑气吸入对中枢神经系统、自主神经系统和心血管系统的影响。TP（总功率）、平均HRT、LF、HF、标准化LF、标准化HF、LF/HF比、血压、心率、每搏输出量、心输出量、总外周阻力和BIS在吸入30%笑气和听莫扎特，巴赫，对照组TP有升高趋势，而实验组TP有降低趋势，表明自主神经活动受到抑制。对照组平均HRT无明显变化，实验组平均HRT由68.0±10.5次/分降至64.1±8.9次/分。在实验组中观察到标准化HF增加。与此相反，正常LF和LF/HF比值在笑气吸入镇静和听治疗音乐期间降低。收缩压、舒张压和平均血压无显著变化。实验组心率由68.0±10.5次/分降至64.1±8.9次/分，BIS值略有下降。TP> 1000ms^2组和TP> 2000ms^2组也有类似的变化趋势。结果提示，心理镇静与听康复音乐相结合，可使交感神经活动降低，副交感神经活动加快。

We have performed dental treatment in patients with dental phobia in the relaxation dental clinic of our hospital since 2002. The purpose of the present study was to investigate the effects of psychosedation with the healing music and nitrous oxide inhalation on the central nervous system, the autonomic nervous system, and the cardiovascular system.Twenty healthy young adult volunteers participated in the study. TP (Total Power), Mean HRT, LF, HF, normalized LF, normalized HF, LF/HF ratio, blood pressure, heart rate, stroke volume, cardiac output, total peripheral resistance and BIS (Bispectral Index) were measured by means of APG Heart Rater SA-3000P, Portapres Model 2, and BIS monitor during 30% nitrous oxide inhalation and listening to the healing music composed by Mozart, Bach, and Vivaldi.TP tended to increase in the control group, but it was apt to decrease in the experiment group, which indicated the depression of the autonomic nervous activities. Although Mean HRT did not change in the control group, it decreased significantly from 68.0±10.5 bpm to 64.1±8.9 bpm in the experiment group. An increase of normalized HF was observed in the experiment group. In contrast with this, normalized LF and LF/HF ratio were reduced during nitrous oxide inhalation sedation and listening to the healing music. No significant changes in systolic diastolic and mean blood pressure were recorded. However, heart rate decreased significantly from 68.0±10.5 bpm to 64.1±8.9 bpm and slight reduction of BIS values were recognizedin the experimental group. The similar tendency was shown in the group of TP more than 1000ms^2 and the group of TP more than 2000ms^2.These results suggested the combination of psychosedation and listening to the healing music brought about the depression of sympathetic nerve activities and the acceleration of parasympathetic nerve activities.