Controlling cell polarity and asymmetric cell division in space and time

这个项目旨在增加我们对细胞如何分裂的理解。不对称细胞分裂是一种特殊的细胞分裂形式，对所有生物体的发育至关重要。卵母细胞的两次减数分裂是不对称细胞分裂的极端例子，它允许染色体含量减少，同时保留发育所必需的细胞质外衣。成功的非对称细胞分裂需要细胞周期事件与细胞极性的整合。了解这是如何实现的，将提高我们对如何在妇女、濒危物种和具有商业价值的动物身上产生健康胚胎的理解。

This project seeks to increase our understanding of how cells divide. Asymmetric cell division is a specialised form of cell division essential for the development of all organisms. The two meiotic divisions of the oocyte are extreme examples of asymmetric cell division that allow a reduction in chromosome content while retaining cytoplasmic vestments necessary for development. Successful asymmetric cell division requires the integration of cell cycle events with cell polarity. Understanding how this is achieved would improve our understanding of how to generate a healthy embryo in women, endangered species and in animals of commercial importance.