hemodynamics of the veno-arterial extracorporeal membrane oxygenation in cardiogenic shock - function and convalescence of the myocardium

本研究的目的是研究和量化VA ECMO治疗对心源性休克患者的血流动力学影响。为此，将在一项随机对照试验中对约40例患者在住院期间进行ECMO治疗期间的有创和无创血流动力学测量。拟实现以下次级目标：1.）确定不同ECMO流速下的心脏功（压力-容积曲线）2.）确定住院期间ECMO应用不同阶段的心血管工作负荷。3.）第三章与侵入性测量相比，验证3D回波的准确性。

The aim of this study is to investigate and quantify the hemodynamic effects of VA-ECMO therapy in patients in cardiogenic shock. For this purpose, invasive and non-invasive hemodynamic measurements during ECMO therapy during hospitalization will be performed on approximately 40 patients in a randomized controlled trial. The following sub-objectives are to be achieved: 1.) To determine cardiac work (pressure-volume curves) at different ECMO- flow rates 2.) Determination of the cardiovascular workload during different phases of the ECMO application during the hospital stay. 3.) Validation of the accuracy of the 3D echo in comparison to invasive measurements.