课题基金 / 基金详情

Novel Fluorinated Bioorganic Molecules for the 21st Century

Novel Fluorinated Bioorganic Molecules for the 21st Century
21 世纪的新型氟化生物有机分子
批准号:
09044277
负责人:
TAKEUCHI Yoshio
金额:
$4.1万
依托单位国家:
日本
项目类别:
Grant-in-Aid for international Scientific Research
财政年份:
1997
资助国家:
日本
项目状态:
已结题
起止时间:
1997 至 1998

项目摘要

项目成果

TAKEUCHI Yoshio的其他基金

相关文献

中文摘要
翻译
这个名为“面向21世纪的新型氟化生物有机分子”的国际合作项目始于1997年,由日本富山医科大学的竹内义雄教授担任首席研究员,美国国立卫生研究院的Kenneth L.Kirk博士、德国威斯特法里斯-威廉姆斯大学的Guenter Haufe教授、德岛文理大学的Toshio Satoh教授、富山国立理工学院的小谷忠志教授、富山医科大学的柴田信夫博士和Tamiko Takahashi博士担任共同研究人员。另外两名共同研究人员,美国洛斯阿拉莫斯实验室(Centralia College)的西格弗里德·洛德维希教授和富山医科大学的木原雅之博士,在1997年底慷慨增加拨款时,被邀请参加这个项目。该项目资助的协作工作国际和国内旅行次数概述如下(1997/1998年)。从日本到美国(4次);从日本到德国(4次);从美国到德国(2次);从美国到日本(3次);从德国到日本(1次);以及日本国内旅行(6次)。作为项目参与者旅行的一部分,每个来访的合作者都介绍了他/她的最新研究成果。此外,这些旅行使科学交流成为可能,提供了与正在进行的研究有关的信息,并允许讨论时间要求、主题和未来合作的风格。由于这种交流,这些研究人员在1997/1998年共发表了60篇科学论文,并在国际和国内科学会议上作了100多次发言。
英文摘要
This international joint project between Japan-USA-Germany entitled "Novel Fluorinated Bioorganic Molecules for the 21st Century" was started in 1997 with Prof.Yoshio Takeuchi of Toyama Medical and Pharmaceutical University as the head investigator, Dr.Kenneth L.Kirk of NIH, USA, Prof. Guenter Haufe of Westfalische-Wilhelms University, Germany, Prof. Toshio Satoh of Tokushima Bunri University, Prof. Tadashi Kometani of Toyama National College of Technology, Drs.Norio Shibata and Tamiko Takahashi of Toyama Medical and Pharmaceutical University as co-investigators. Two additional co-investigators, Prof.Siegfried Lodwig of Los Alamos Laboratory (Centralia College), USA, and Dr.Masayuki Kirihara of Toyama Medical and Pharmaceutical University were invited to this project when the amount of the grant was generously increased at the end of 1997. The numbers of international and domestic trips for collaborative work funded by the project for the period (1997/1998) are summarized as follows. Travels from Japan to USA (4) ; from Japan to Germany (4) ; from USA to Germany (2) ; from USA to Japan (3) ; from Germany to Japan (1), and domestic travels in Japan (6). As part of these travels by the participants of the project, each visiting collaborator has presented his/her up-to date research results. In addition, scientific exchanges made possible by these trips have provided information dealing with on-going research, and allowed discussions of time requirements, themes, and the style of future collaborations. As a result of such interchanges, a total of 60 scientific papers were published by these investigators for 1997/1998, and a total of more than 100 presentation were made at international and domestic scientific meetings.
期刊论文(21)
专著(0)
科研奖励(0)
会议论文
Y.Takeuchi et al.: "Efficient Synthesis of A New, Highly Versatile Chiral Derivatizing Agent, α-Cyano-α-fluoro/p-tilylacetic Acid (CFTA)" Chem.Commun.1998. 365-366 (1998)
Y.Takeuchi 等人:“新型、高度通用的手性衍生剂 α-氰基-α-氟/对苯乙酸 (CFTA) 的高效合成”Chem.Commun.1998 (1998)。
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H.Yokoyama et al.: "Asymmetric Synthesis of Chiral 2-Fluorinated 1,3-Propanediols and its Application to the Preparation of Monofluorinated Chiral Synthon" Tetrehedron Lett.39. 7741-7744 (1998)
H.Yokoyama 等人:“手性 2-氟化 1,3-丙二醇的不对称合成及其在单氟化手性合成子制备中的应用”Tetrehedron Lett.39。
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H.Yokoyama et al: "Asymmetric synthesis of chiral 2-Fluorinated 1,3-Propanediols and Its Application to the Preparation of Monofbcorinated chiral synthon" Tetrahedron Lett.39. 7741-7744 (1998)
H.Yokoyama等人:“手性2-氟化1,3-丙二醇的不对称合成及其在单纤手性合成子制备中的应用”Tetrahedron Lett.39。
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Y.Takeuchi et al.: "Chemistry of alpha-Fluoro-alpha-amino Acids : The First Synthesis of alpha-Fluoro-glycine-containing Dipeptides" Chem.Pharm.Bull.46. 1062-1064 (1998)
Y.Takeuchi 等人:“α-氟-α-氨基酸的化学:含α-氟-甘氨酸二肽的首次合成”Chem.Pharm.Bull.46。
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共 21 条
    Design & Synthesis of Novel Enantioselctive Fluorinationg Agents
    Efficient preparation of a highly versatile chiral derivatizing agent, CFTA, for determination of absolute configurations.
    Development of Electrophilic and Enantioselective Fluorinating Agents based on Fine Chemisty Design
    Synthesis and Utilization of Fluorine-containing Chiral Building Blocks for Development of the New Type of Drugs