CLINICAL EFFECTS OF BLOOD PRESSURE BIOFEEDBACK ON ESSENTIAL HYPERTENSION

本研究旨在探讨血压生物反馈（BF）治疗原发性高血压的临床效果，并探讨心理应激试验对心血管反应的影响。本研究以30例原发性高血压门诊患者为研究对象（男性10例，女性20例），随机分为A组和b组。B组患者在对照组期间自行监测血压，随后接受与a组相同的BE治疗。a组患者在治疗期间血压显著降低17*18/8*7 mmHg （p< 0.01）。B组患者在治疗期间血压显著降低20*15/9*7 mmHg （p< 0.05）。同时，A组和b组的心理应激测试（心算任务）引起的心血管反应被BE治疗显著抑制。另一项研究旨在评估原发性高血压患者对心理应激的反应性。我们研究了10例高血压门诊患者心算任务（MAT）和镜画试验（MDT）时血液动力学和内分泌学的变化。MAT期间血压升高37.8*11.1/17.5*3.1 mmHg (p< 0.01)， MDT期间血压升高41.0*9.4/21.2*3.9 mmHg （p< 0.01）。MAT和MDT期间血浆去甲肾上腺素和肾上腺素水平也显著升高（p< 0.01）。虽然去甲肾上腺素对MAT和MDT的反应相似，但肾上腺素对MAT的反应大于对MDT的反应。本研究结果表明，MAT可能比MDT更能激活交感神经肾上腺髓质系统。

The purpose of this study is to discuss the clinical effects of blood pressure biofeedback (BF) on essential hypertension, and to investigate the modification of cardiovascular responses induced by the mental stress test.The subjects of this study were thirty outpatients with essential hypertension (10 men and 20 women), which were randomly assigned to group A or B.Subjects of group A underwent four BE treatment sessions. Those of group B monitored their blood pressure by oneself during the control period, and later underwent the same BE treatment as group A.There were significant blood pressure reduction by 17*18/8*7 mmHg (p<.01) during the treatment period in group A.in group B, there were no significant changes during the control period but significant blood pressure reduction by 20*15/9*7 mmHg (p<.05) during the treatment period. And, the enhanced cardiovascular responses induced by the mental stress test (the mental arithmetic task) were significantly suppressed by the BE treatment in both group A and B.Another study aimed to evaluate the reactivity to psychological stress in patients with essential hypertension. We investigated the hemodynamic and endocrinological changes during the mental arithmetic task (MAT) and the mirror drawing test (MDT) in 10 hypertensive outpatients. There were significant blood pressure elevations by 37.8*11.1/17.5*3.1 mmHg (p<.01) during MAT, and by 41.0*9.4/21.2*3.9 mmHg (p<.01) during MDT, respectively. The plasma levels of Norepinephrine and Epinephrine also increased significantly (p<.01) during both MAT and MDT.Although Norepinephrine had similar response to both MAT and MDT, Epinephrine had more response to MAT than to MDT.By the results of this study, it was indicated that the sympathoadrenomedullary system might be more activated by MAT than MDT.