Chemical Study on Industrial Products for Medicinal Resources

Vitis Vinifera“Kyohou”的软木被作为废物产品从生产者中得到。在寻找新的医学资源的过程中，软木被强迫使用。软木塞加了11部小说的甲醇提取物，一部小说的苯乙烯修剪剂，一部小说的苯乙烯二聚体，和一部小说的苯乙烯二聚体，如许多已知的寡苯乙烯。（+）的生物起源反应-ε-葡萄素，一种已知的苯乙烯二聚体和一种主要的宪法，到小的生物活性寡苯乙烯已经研究过。（+）-ε-Viniferin赋予了三种不同的苯乙烯二聚体与（+）-ε-Viniferin不同的碳骨架。（+）-ε-葡萄素与荷沙丁过氧化物酶和羟基过氧化物释放（-）-维生素B和（+）-维生素C，苯乙烯四ramer的反应。（+）-维生素A和（-）-维生素B展示了强大的抗附着活动，反对壳。Furthermore，（+）-vitisin C展示了强有力的抑制of the contractile responses of rabbit aorta in an endothelium-dependent manager by producing NO due to facilitate intracellular CA在endothelial cells中的移动性。

The cork of Vitis vinifera 'Kyohou' was given from the cultivator as waste products. In the course of seeking for new medicinal resources, the cork was forcused on.1. The methanol extract of the cork gave 11 novel stilbene tetramers, a novel stilbene trimer, and a novel stilbene dimer as well as many known oligostilbenes.2. The biogenetic reactions of (+)-ε-viniferin, a known stilbene dimer and a major constituent, to minor biologically active oligostilbenes were studied. Acid-catalyzed reactions of (+)-ε-viniferin gave three kinds of stilbene dimer having carbon skeletons different from (+)-ε-viniferin. A reaction of (+)-ε-viniferin with horseradish peroxidase and hydrogen peroxide gave(-)-vitisin B and (+)-vitisin C, stilebene tetramers.3. (+)-Vitisin A and (-)-vitisin B showed strong anti-attachment activity agaist shells. Furthermore, (+)-vitisin C showed strong inhibition of the contractile responses of rabbit aorta in an endothelium-dependent manner by producing NO due to facilitate intracellular CAィイD12+ィエD1 mobilization in endothelial cells.