Insolubilized Properties of Collagen as Artificial Periodontal Membrane Irradiated by Plasma

具有生物相容性的人工牙是失去天然牙齿的老年人所需要的。近年来，陶瓷植入体已被部分应用，但其难以制造出复杂的形状，并且从动力学角度来看不适合。在本研究中，考虑到天然牙在牙周膜上的良好作用，研究了胶原蛋白作为人工牙周膜的不溶性。人工膜包被磷灰石-胶原复合材料，经等离子体和紫外线照射，在大鼠体内具有良好的生物相容性。然而，由于复合材料和人工牙周膜的力学性能不足以应用，进一步的研究正在进行中。

Biocompatible artificial teeth are desired especially by the old aged,who have lost their natural teeth.Recently, ceramic implants have been used in part, but they ar hard to make a complex form and not suitable from a dynamical view point. In this study, considering that natural teeth act well their roles with periodontal membrane, insolubilized properties of collagen as artificial periodontal nembrane were examined.Apatite-collagen composites coated with artificial membrane and irradiated by Plasma and UV-ray showed good biocompatibility in rat. However, since mechanical properties of the composites and artificial periodontal membrane were not enough to apply, further investigations are in progress.