Studies on lithotripsy with the use of electrohydraulic shock wave and molding of fibrin coaglum for intrhepatic stone.

采用纤维蛋白凝固法和电液冲击波碎石术对肝内胆管结石进行了实验研究和新的临床研究。1987年，用实验性胆道模型讨论了不同胆汁和温度条件下纤维蛋白凝固物在胆道内的硬度和溶解情况。但是，这项实验很难继续下去。因为在临床使用中，纤维蛋白原的抗原性对人类是有害的。1988年，电液冲击波碎石术治疗肝内胆管结石尝试临床应用。从临床试验的结果来看，对于肝内结石复发或残留结石的患者，用该方法可以完全清除各种类型的肝内结石。该方法安全可靠，术中无任何并发症和麻烦。但是，由于病例数量太少，很难得出这种方法在临床上有用和有效的结论。从本研究的结果来看，电液冲击波碎石和球囊探条扩张治疗肝内胆管结石是有效的，但需要进一步研究长期效果和更多的病例来完成本研究。

Experimental and new clinical investigation for intrahepatic stone was studied with the fibrin coaglum molding method and electrohydraulic shock wave lithotripsy. In 1987, rigidity of fibrin coagulum in biliary tract and dissolution on of fibrin coagulum in various conditions of bile juice and temperature was discussed with the experimental biliary tract model. But ,it is difficult to continue this experiment . Because, antigenicity of the fibrinogen is harmful for the human being in the clinical use of them. In 1988, electrohydraulic shock wave lithotripsy in patient with intrahepatic stone was tried to use clinically. From the results of this clinical trials, various types of intrahepatic stone were destroyed completely with this method for the patient of recurrence of intrahepatic stone or remnant stone. This method is safety without any trouble and complication at the time of operation. But, it is difficult to conclude that this method is useful and effective in clinical use, Because the number of this case is too small. On the other hand, balloon bougie for intrahepatic bile duct stricture was used in two cases and it is effective in these cases.In conclusion, from the results of this study, electrohydraulic shock wave lithotripsy and balloon bougie dilation for intrahepatic stone is useful and effective, but further study of long term result and more case is necessary to complete this study.