Fundamental Study of Hydroxy-apatite-coated Metal for Artificial Joint Use.

本研究将HA涂层SUS 316L不锈钢在负重条件下植入犬股骨。对种植体-骨界面区域进行组织学评估。采用手相喷涂技术对SUS 316L不锈钢种植体髓内棒表面进行HA涂层处理。植入后1、3、12个月处死。组织学切片显示，在3个月和12个月时，HA涂层种植体的尖端直接与致密的骨小梁接触，没有任何纤维组织。然而，在12个月的切片中发现HA层部分被移除。另一方面，在12个月时，HA涂层的植入物在去骨的犬股骨末端被厚纤维组织包围。采用新技术热分解法将钛和羟基磷灰石包覆钛植入犬体内。对种植体-骨界面的力学强度进行了分析。羟基磷灰石涂层的钛骨界面强度高于普通钛骨界面。

In the present study, HA coated SUS 316L stainless steel was implanted in canine femur under load-bearing conditions. The implant-bone interface regions were assessed histologically. The intramedullary rod surfaces of SUS 316L stainless steel implants were coated with HA by palsma spraying techniques. The dogs were sacrificed at 1, 3, and 12 months after implantation.Histological sections revealed that the tips of the HA coated implants were in directly contact with dense bony trabecula without any fibrous tissue at 3 and 12 months. While, it was found that HA layer was partially removed in the twelve-month section.On the other hand, the HA coated implant in the osteotomized end of the canine femur was surrounded with thick fibrous tissue at 12 months.Pare titanium and HA coated TI by a new Technique Theremal decomposition method were implanted in canine. The mechamical strength of the implant-bone interface was analysed. The strength of HA coated Ti-bone interface was stroger than that ofti-bone interface.