Clinical Application of Dipole Tracing Method Estimating Electric Generator Source in the Brain.

偶极跟踪系统是我们开发的一种非侵入性方法，可以从传统的脑电图记录中估计人脑中的电源。我们在瑞典乌普萨拉大学医院对三名顽固性癫痫发作患者进行了研究工作。从研究工作中得出以下结论。我们估计偶极子的位置和矢量矩的间隔凸锐波记录（用传统的脑电图技术）从右额颞区部分复杂癫痫患者。当将头部模型中的偶极子位置与MRI扫描相比较时，发现大多数锐波偶极子位于右侧海马区。以前的长期硬脑膜下记录显示该区域有癫痫发作。这些发现将发表在1990年的《神经科学快报》上。我们从硬脑膜下电极的三维x射线图像中获得了校正因子，并估计了硬脑膜下电极上人工引发的偶极子的位置。这些发现将发表在1990年的《IEEE生物医学工程学报》上。

Using the Dipole Tracing System, which we have developed and is non-invasive method to estimate electrical sources in the human brain from conventional EEG recordings, we have performed research works on three patients suffering from intractable epileptic seizure in University Hospital Uppsala, Sweden. The following findings were obtained from the research works.We have estimated dipole locations and vector moments of interictal convexity sharp waves recorded (with conventional EEG technique) from the right fronto-temporal region in a patient with partial complex seizures. When the dipole locations in the head model were compared to MRI scans, the majority of the sharp wave dipoles were found to be located in the right hippocampal area. Previous long-term subdural recording had shown seizure onset in this area. These findings will be published in Neuroscience Letters in 1990.We have obtained correction factors from three-dimensional X-ray images of the subdural electrodes and estimated locations of the dipoles artificially elicited on the subdural electrodes. These findings will be published in IEEE Transaction of Biomedical Engineering in 1990.