Psychophysiological study of the mechanism of REM-NREM rhythm.

我们研究了影响睡眠起始REN期（SOREMP）出现率的因素，SOREMP是由睡眠中断方法引起的。1991年，我们对SOREMP进行了重点研究，探讨了SOREMP过程中的主观体验和生理背景。本摘要描述了1991年进行的研究结果。受试者在第一或第三个睡眠周期中经历了40分钟的非快速眼动睡眠后，被强迫唤醒，睡眠中断60分钟。该时间表以71.9%的高比率产生睡眠起始REM期（SOREMP）。我们成功地诱发了6次孤立性睡眠麻痹（ISP）。除1例外，所有ISP发作均发生于SOREMP，表明ISP与SOREMP之间密切相关。我们在ISP期间记录口头报告和多导睡眠图（PSG）。所有患有ISP的受试者都经历了无法移动，并且知道在实验室中说谎。除一人外，所有人都报告了幻觉和不愉快的情绪。PSG在ISP期间的特征在于W/REN解离状态，即：即大量的α脑电图和持续的肌肉张力减退。ISP不同于清醒梦、夜间惊恐发作和REM睡眠行为障碍等分离状态，我们还研究了ISP中断对直肠温度（RT）的影响。中断后，RT急剧下降，以及在第一次睡眠开始后。它仍然低于两个小时，比相应的基线夜晚。因此，曲线谷值降低，谷位前移。在中断的夜晚，RT下降中断后并不伴随着任何增加慢波睡眠。因此，我们认为RT下降与SWS量之间没有直接关系。我们比较了使用SOREMP和不使用SOREMP的夜间RT模式。在SOREMP夜间，RT往往低于SOREMP夜间在第二次睡眠开始。这种SOREMP的出现可能有生理原因。

We have investigated the factors influencing the appearance rate of sleep onset REN period(SOREMP), which is elicited by a sleep interruption method. in 1991, we focused on the SOREMP and exalued the subjective experiences and the physiological background during SOREMP. This abstract describes the results conducted in 1991.Subjects had their sleep interrupted for 60 minutes by forced awakening when 40 minutes of NREM sleep had elapsed in the 1st or 3rd sleep cycle. This schedule produced sleep onset REM period(SOREMP)at a high rate of 71.9%. We succeeded in eliciting six episodes of isolated sleep paralysis(ISP). All episodes of ISP except one occurred from SOREMP, indicating a close correlation between ISP and SOREMP. We recorded verbal reports and the polysoinograi(PSG)during the ISP. All the subjects with ISP experienced Inability to move and were aware of lying in the laboratory. All but one reported hallucinations and unpleasant emotions. PSG during ISP were characterized by a W/REN dissociated state, i. e, abundant alpha EEG and persistence of muscle atonia. ISP differs from other dissociated states as lucid dreaming, nocturnal panic attacks, and REM sleep behavior disorders.We also Investigated the effects of the Interruption on rectal temperature(RT). Following interruption, RT decreased drastically as well as after the first sleep onset. It remianed lower, for two hours, than the corresponding baseline night. Consequently, the value of the curve-trough lowered and the position of the trough advanced. In interrupted nights, the RT fall after interruption was not accompanied by any increase In slow wave sleep. So we suggest no direct relationship between RT fall and amount of SWS. We compared RT patterns between nights with SOREMP and without SOREMP. In SOREMP nights, RT tended to be lower at the second sleep onset than SOREMP nights. There may be physiological causes for this SOREMP appearance.