Correlation between procedural memory and neural activity in monkey putamen.

在猴壳核记录单个神经元的活动，以研究操作杆挤压行为中视觉和运动信息处理的神经特征。在接受测试的615个神经元中，9.8%(60/615)的神经元对视觉和/或接触酒吧前的一段强制延迟时间内看到物体有反应。在反应时间任务中，很少有神经元在看到物体时做出反应，在该任务中，当物体出现时，可以接触到杆状物体以立即按压。大多数神经元在强制延迟期内有反应。视觉相关的神经反应取决于物体的性质，不同物体的反应幅度不同。视觉反应潜伏期为300~400ms。在615个神经元中，有16.6%(102个)对手臂运动如屈曲和/或伸展有反应。这种与运动相关的神经活动与每个单杠压力机的运动并不相关。与运动相关的反应似乎更多地受到任务装置和任务范式的启发。这些结果表明，壳核神经元可能在适当的条件下编码视觉设定的相关条件。

Single neuron activity was recorded in the monkey putamen to investigate neural characteristics of visual and motor information processing during operant bar press behavior. Of 615 neurons tested, 9.8 % (60/615) responded to sight of objects during visual and/or an enforced delay period before access to the bar. Few neurons responded at the sight of objects during the reaction time task in which the bar could be accessed for pressing immediately upon presentation of an object. Most neurons responded during the enforced delay period. The vision related neural responses depended on the nature of the objects, and the amplitude of the responses differed for different objects. The latency of the visual responses was 300-400 ms. Of the 615 neurons, 16.6 % (102) responded to arm movement such as flexion and/or extension for bar pressing. Such motor related neural activity did not correlated with the movement for each individual bar press. Motor related responses appeared rather to be affected by illumination of the task apparatus and task paradigms. These results suggest that the putamen neurons might encode visually set related conditions in appropriate conditions.