The Experimental Allotransplantation of Trachea and Bronchus in dogs

同种异体气管移植仍有许多问题需要解决。移植物的血液供应是其存活的最重要因素之一。为探讨网膜固定术增加移植气管血供的效果，用12只犬进行了同种异体气管移植实验。在静脉全麻下，暴露供犬颈段气管，切取5段气管软骨，移植于受体犬颈段气管同一部位。同种异体移植后，将带蒂大网膜移植于移植物周围，以获得有效的血供。实验犬分为两组：A组网膜血供良好（n=6），B组网膜血供不良（n=6）。然而，A组的狗比B组的狗存活更长时间。A、B组平均存活天数分别为34.6 × 6.80天和18.4 × 6.47天，提示网膜固定法移植气管的血供是延长移植气管存活时间的重要因素。

There still remain many problems to be solved on allotransplantation of trachea. The blood supply to the graft is one of the most important factors for its survival. This study was carried out to evaluate the effects of omentopexy that will be more increase of blood supply to the graft.Twelve dogs were used for this experiment of allotransplantation of trachea. Under intravenous general anesthesia, the cervical trachea in the donor dog was exposed and 5 segments of tracheal cartslage were excised, and then these grafts were transplanted at the same portion of the cervical trachea in the recipient dog. After the allotransplantation, the omental pedicle was transplanted around the graft, to get the effective blood supply. The canines were divided into two groups: group A; good blood supply in omentum (n=6) and group B; poor supply in omentum (n=6)White coating was observed inside the graft in all dogs with bronchofiberscopy. The dogs of group A, however, had survived longer than the dogs of group B. The mean survival days of group A and B were 34.6 * 6.80 days and 18.4 * 6.47 days, respectively.These results suggest that the blood supply to the allograft of trachea by omentopexy is important factor for the extension of its survival time.