Hypertonic saline for acute cerebral swelling following multiple trauma with severe head injury.

我们建立的制度如下：用数字压力导管（型号110-4E）测量压力，并将其转换成电信号（型号420）。信号放大（AG-601G）并记录在热记录仪（PAT-1200）上。此外，信号将被集成（由EI-601G）并存储在软盘中。同时，以同样的方式处理动脉血压数据，计算脑综合灌注压并存储在软盘中。1990年，建立了基本测量系统。在1991年，大部分的努力都是为了获得测量综合压力的最佳时间常数。多发伤患者脉搏变化多样（150 ~ 50次/分），且变化较快。初始时间常数设为1秒，使用此时间常数对数据进行标准化处理，会产生数据波动。对时间常数3、5、8、10进行了计算，3秒是该数据处理系统的最佳时间常数。在此基础上，建立了最终的系统和程序。根据这个研究项目，我们可以通过这个系统来评估压力对大脑的影响。我们将能够将该系统应用于临床病例，正如我们在最初的4年计划中所计划的那样。

The system which we have established is as followed ; measuring the pressure with digital pressure catheter (model 110-4E) and chnage it into electric signals (by model 420). Amplified the signals (by AG-601G) and record them on thermal recorder (PAT-1200). Also the signals will be integrated (by EI-601G) and stored them in a floppy disk. Simultaneously, data of arterial blood pressure will be processed in a same way and integrated cerebral perfusion pressure will be calculated and stored them in a floppy disk. In 1990, basic masureing system were established. In 1991, most of efforts were shared to obtain an optimal time constant for measurement of integrated pressure. Patients with multiple trauma have variety of pulse rate (150-50/min.) and it changes quite rapidly. Initially time constant was set at 1 sec. with this time constant for standadized the data, data fluctuation was occured. Time constant 3, 5, 8, 10 have been evaluated and 3 second was the best time constant for this data processing system. Obtaining this value the final system and its program was established.According to this research project, the system by which we can eveluate pressure effect across time on brain becomes avaiable. We would be able to apply the system to clinical cases as we have planed in the initial 4 years schedule.