Relationship between Gastrointestinal Myoelctric Activity and Portal Venous Flow before and after Truncal Vagotomy, Gastrectomy with or without Vagotomy.

禁食期间，胃肠道呈周期性活动，移行性肌电复合体(MMC)在胃和十二指肠有规律地出现，并向远端传播。摄食使MMCs明显受阻，然后整个肠道出现均匀的电活动。根据胃十二指肠的活动，空腹门静脉血流(PVF)出现轻微波动。餐后PVF变化与肠道活动密切相关。进食后，PVF迅速升高，30min内达到平台期。空肠MMC恢复所需时间(MMC抑制时间)与PVF增加时间(平均空腹PVF+2SD)呈显著正相关。切断躯干迷走神经(TV)后，小肠内可见MMC周期性出现，禁食24 h后，胃内仍有少量MMCs出现。摄食使肠道MMCs消失，由禁食模式转变为摄食模式，摄食后PVF的变化呈现出多种模式。一些餐后PVF迅速增加，而另一些非常缓慢。MMC抑制时间和PVF增加时间在每天和狗之间都不同。MMC抑制时间与PVF增加时间之间无相关性。结论：迷走神经切断后肠运动障碍影响肠道循环，导致门静脉供血障碍。远端胃切除加或不切断迷走神经对肠运动和循环的影响尚需进一步研究。

During the fasting, gastrointestinal tract showed periodic activity, and the migrating myoelectric complex (MMC) occurred regularly in the stomach and the duodenum, and propagated distally. Feeding dramatically disrupted MMCs, then uniform electrical activity of the fed pattern took place in the entire intestine.The fasting portal venous flow (PVF) showed slight fluctuation, according to the gastroduodenal activity. Postprandial changes in PVF were closely correlated with intestinal activity. After ingestion of meal, PVF soon elevated and reached plateau within 30min. Period of increased PVF persisted for more than 2 hours, then the PVF gradually decreased to the fasting value.There was significant correlation between the time required for reappearance of MMC in the upper jejunum (MMC-inhibition time) and the PVF-increasing time (<mean fasting PVF + 2SD).After truncal vagotomy (TV), periodic appearance of MMCs ws observed in the small intestine, while few MMCs occurred in the stomach even after 24-h fasting. Feeding abolished MMCs from the intestine, converting the fasting pattern to the feeding pattern.After TV, changes in PVF after feeding showed a various patterns. Some postprandial PVF increased rapidly, while another very slowly.Both MMC-inhibition time and PVF-increasing time varied in each day and between dogs. The correlation between MMC-inhibition time and PVF-increasing time was not seen after TV.In conclusion, motility disorders after vagotomy influence on intestinal circulation, causing a disturbed portal blood supply to the liver.To clarify the effects of distal partial gastrectomy with or without vagotomy on intestinal motility and circulation, Further studies on the intestinal myoelectric activity and PVF will be required.