The evaluation of the preserved lung using NMR Spectroscopy.

为了评估器官保存液中钾离子浓度对肺保存的影响，本研究制作了四种类型的溶液。这些保存液由钠离子和钾离子作为阳离子（Na^+, 155 mmoI, K^+；溶液1为0，Na^+；溶液1为150，K^+；溶液2为5，Na^+；溶液2为20，K^+；溶液3为135，Na^+; 0, K^+；溶液4为155）和磷酸盐离子作为阴离子与葡萄糖组成，它们具有相同的渗透压、相同温度下相同的pH值和相同的缓冲作用。用这些溶液在7^+C下保存肺24小时，并在全氟化学乳剂大鼠肺灌注系统中进行评估。低钾溶液（但不是零钾）肺动脉流量恢复率较好。另一方面，在高钾溶液中，湿干比保持较低。各组肺静脉流出液潮气量和氧张力恢复率无显著性差异。综上所述，钾离子浓度在该系统的肺保存中不起主要作用。

To evaluate the influence on lung preservation of potassium ion concentration in an organ preservation solution, four types of solutions were produced for the present study. These preservation solutions consisted of sodium and potassium ions as cation (Na^+ ; 155 mmoI, K^+ ; 0 in solution 1, Na^+ ; 150, K^+ ; 5 in solution 2, Na^+ ; 20, K^+ ; 135 in solution 3, Na^+ ; 0, K^+ ; 155 in solution 4), and phosphate ion as anion, with glucose, They possess the same osmolarity, the same pH in the same temperature and the same buffer action. The lungs were preserved at 7^+C with these solutions for 24 hours and evaluated in a rat lung perfusion system with perfluorochemical emulsion.The recovery rates of pulmonary arterial flow were better in low (but not zero) potassium solutions. On the other hand, wet-to-dry ratios were kept lower in high potassium solutions. The recovery rates of tidal volume and oxygen tension of pulmonary venous effluent showed no significant difference in each group. In conclusion, potassium ion concentration does not play a major role in lung preservation in this system.