Relationships between eruptive force and blood pressure, and colloid osmotic pressure
Relationships between eruptive force and blood pressure, and colloid osmotic pressure
批准号:
02670844
负责人:
CHIBA Mototsugu
金额:
$1.66万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for General Scientific Research (C)
财政年份:
1990
资助国家:
日本
项目状态:
已结题
起止时间:
1990 至 1992
中文摘要
1. 使用血压计(UR-5000, UEDA)测量未麻醉大鼠的动脉血压。收缩压、舒张压和平均血压均为156(±±)。[)9, 109(] [a] .+-。[1] [6] [1] [5][) 7mmhg。氨基甲酸乙酯麻醉下,大鼠门牙出疹率降至控制值的83%。2. 切牙髓内组织液胶体渗透压为5.0 ~ 14.3 mmHg,低于血清(17 mmHg)。静脉注射高渗葡聚糖溶液(20-30%)对出疹率无影响。3. 火山喷发速率为550(±±)。[)127妈妈/24小时和548(]SY.+-。[]聚氨酯和氟烷麻醉分别为137妈/24 h。直接测尾中动脉平均血压为77(]SY.+-。[)16毫米汞柱和78毫米汞柱。[]聚氨酯和氟烷麻醉下分别为12 mmHg。研究发现,出疹率与平均血压有显著的相关性。4. 观察肾上腺素能药物对平均血压、出疹率和出疹力的影响。静脉注射肾上腺素或去甲肾上腺素后,平均血压随出疹率和出疹力的增加而增高。静脉注射肾上腺素或异丙肾上腺素后,平均血压下降,出疹率和出疹力明显降低。爆发率和爆发力的降低及其恢复过程与平均血压的变化无关。5. 提示全身动脉血压与大鼠切牙的出牙率和出牙力有密切的关系,尽管这些变化的时间过程和数量并不总是平行的。
英文摘要
1. Arterial blood pressure was measured in unanaesthetized rats using a hemadynamometer (UR-5000, UEDA). The systolic, diastolic and mean blood pressures were 156(〕SY.+-.〔)9, 109(〕SY.+-.〔)6 and 124(〕SY.+-.〔)7 mmHg respectively. the eruption rate of the rat incisor decreased to 83% of the control value under urethane anaesthesia. 2. colloid osmotic pressure in the tissue fluid within the incisor pulp ranged from 5.0-14.3 mmHg which was lower than that in the serum (17 mmHg). Intravenous injection of hypertonic dextran solution (20-30%) did not affect the eruption rate. 3. The eruption rates were 550(〕SY.+-.〔)127 mum/24 h and 548(〕SY.+-.〔)137 mum/24 h under urethane and halothane anaesthesia respectively. The mean blood pressures were also measured directly from the mid-tail artery which were 77(〕SY.+-.〔)16mmHg and 78(〕SY.+-.〔)12 mmHg under urethane and halothane anaesthesia respectively. A significant correlation was found between the eruption rate and the mean blood pressure. 4. Effects of adrenergic drugs on the mean blood pressure, the eruption rate and the eruptive force were examined.Temporal increase of the mean blood pressure in accord with increases in the eruption rate and eruptive force was observed after intravenous injection of adrenaline or noradrenaline. A decrease of the mean blood pressure and marked reductions of the eruption rate and eruptive force were observed following intravenous injection of adrenaline or isoproterenol. Reductions of the eruption rate and eruptive force and their recovery processes were not associated with changes in the mean blood pressure. 5. It is suggested that there are close relations between the systemic arterial blood pressures and the eruption rates and eruptive forces of the rat incisor, although the time course and quantity of these changes are not always parallel with each other.
期刊论文(3)
专著(0)
科研奖励(0)
会议论文
山口 志津代: "ハロセン麻酔、人工呼吸下におけるラット下顎切歯萌出力に及ぼすアドレナリン作動性薬物の影響" 日本薬理学雑誌. 100. 165- (1992)
Shizuyo Yamaguchi:“肾上腺素药物对氟烷麻醉和人工呼吸下大鼠下颌切牙萌出量的影响”日本药理学杂志 100. 165- (1992)。
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通讯作者:
山口志津代: "ハロセン麻酔、人工呼吸下におけるラット下顎切歯萌出力に及ぼすアドレナリン作動性薬物の影響" 日本薬理学雑誌. 100. 165 (1992)
Shizuyo Yamaguchi:“肾上腺素药物对氟烷麻醉和人工呼吸下大鼠下颌切牙萌出量的影响”日本药理学杂志 100. 165 (1992)。
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S.Yamaguchi: "Effects of adrenergic drugs on the eruptive force of the mandibular incisor in rats anaesthetized with halothane under artificial respiration" Folia Pharmac. Jap.100. 165 (1992)
S.Yamaguchi:“肾上腺素药物对人工呼吸下氟烷麻醉的大鼠下颌切牙萌出力的影响”Folia Pharmac。
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作者:
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通讯作者:
Role of circulatory system in the process of the rat incisor eruption
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批准号:05671558
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.34万
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财政年份:1993
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负责人:CHIBA Mototsugu
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依托单位: