Research of Totally Implantable Linear Pulse Motor-Driven Artificial Heart

动物试验中的完全可移植线性人工心脏我们团队一直在考虑使用线性脉冲电机(LPM)作为驱动源的可能性，并开发了一系列带有该电机的人工心脏模型新开发的可植入线性人工心脏(LAH)有两个血泵，由LPM交替充气和放气，导致推板使血液搏动。LAH直径85毫米*95毫米宽(0.55升总体积)，重1.2公斤。LPM包括作为次要成员的平动件和作为主要成员的两个定子。使用两个直线轴承来支撑它们。定子和动子都是由具有高饱和磁通密度的永磁层叠层制成的。LPM以60-100次/分钟的速度提供50-60牛顿的动能推力，相当于人工心脏所需的速度。使用Windkesel模拟循环系统对LAH的性能进行了评估，结果足以满足人体静止时对流量的要求。最大主动脉压(AOP Max)为141 mm Hg，最大肺动脉压(PAP Max)为28 mm Hg，最大流速为5.1升/分钟。与广岛大学医学院合作，于1993年9月24日进行了绵羊动物试验。实验证实，植入的人工心脏可以在活体内发挥预期的功能。心脏可以正常工作长达两个小时，在设备可以应用于临床之前，开发专家还面临着许多尚未解决的问题，但它已经稳步向最终目标迈进

Totally lmplantable Linear-type Artificial Heart under Animal TestingOur group has been considering the possibility of using a linear pulse motor (LPM) as a driving source, and has developed a series of artificial heart models with the motorThe newly developed implantable linear-type artificial heart (LAH) has two blood pumps, which are inflated and deflated by the LPM alternately, causing a pusher plates to pulsate the bloodThe LAH measures 85 mm in diameter * 95mm wide (0.55 litters total volume) , and weighs 1.2kg. The LPM comprises a flat mover as the secondary member and two stators as the primary member. Two linear bearings are used to support them. Both stators and mover are made of laminated thin layrs of Permendur with high saturation flux density.The LPM provides a kinetic thrust of 50-60 newtons at 60-100 beats per min., the speed required by an artificial heartA Windkessel-type mock circulatory system was used to evaluate the performance of the LAH.The results were good enough to meet the flow rate requirements of a human at rest. Maximum aortic pressure (AoP max) of 141 mmHg, maximum pulmonary arterial pressure (PAP max) of 28 mmHg, and maximum flow rate of 5.1 liters per min. were obtainedIn collaboration with Hiroshima University Medical School, animal testing using a sheep was conducted on September 24 1993. The experiment confimed that the implanted artificial heart could function as expected in a living body. The heart worked properly for up to two hoursThe development profect still faces a number of unsolved problems before device can be applied clinically, but it has been steadily advancing toward the final target