Study and gene ralization of "Oscillator and gate operators model" in vasomotor center

为验证我们的“振荡器和门控器模型”，在清醒自由运动的切口上，分别测定了麻醉大鼠（体重0.2-0.4kg）、猫（2-4kg）和猪（20- 50 kg）在安静和运动时的主动脉压、主动脉神经活动、心交感神经活动（CSNA）和心电图。用聚类程序分析同步CSNA和肾交感神经活动（RNA）的周期性、峰宽和峰位，测量同步CSNA和RNA相对于心电图R波的延迟时间。大鼠、猫和猪的Tc节律模式几乎相同，Tb节律模式随心动间期而变化。压力感受器输入、心率和化学感受器输入均不影响Tc rlythm（8- 12 Hz）。结果表明，Tc节律是中枢起源的共同基本节律，与神经网络的大小和体重无关。在大鼠和猪中，同步化RNA的概率分别在delouy时间为50 ms和180 ms时达到最大值，然后在零附近迅速发展。这些结果表明，门运算符以最大概率打开，而以最小概率关闭。

To examine our "oscillater and gate operator model" aortic pressure, aotic nerve activity, cardiac sympathetic nerve activity (CSNA) and ECG were measured Simultaneously during rest and exercise in conscious freely-moving cuts and separately in anesthetized rats (BW : 0.2-0.4kg), cats (2-4kg) and swines (20-50kg). Periodicity, peak neight and width of synchronized CSNA and renal sympathetic nerve activity (RNA) were analyzed by the cluster program and the delay time of synchronized CSNA and RNA from the R wave of ECG was measured The interval histograms show two modes consisting 8-12Hz (Tc) and cardiacrelated (Tb) rlythms. The modes of Tc rlythm were almost the same in all of the rats, cats and swines whereas the modes of Tb rlythm changed depending on the cardiac intervals. The Tc rlythm (8-12Hz) did not influeced by baroceptor input, heart rate and chemoreeptor inputs. The results indicate that the Tc rlyth is the common fundameutal rlythm of central origin and is independent of the size of neural network and body weight. The probability of synchrouized RNA was maximum at delouy time of 50ms and 180ms in the rats and swines, respectirely, and then deveused rapidly near Zero due to pulsatile beroceptor input. These results suggest that the gate operators oppened at the maxim probability while it closed at the minimum probubility.