Study on factors that transcriptionally regulate the gene encoding an immunodominant antigen expressed specifically in larval stage of Dirofilaria immitis.
Study on factors that transcriptionally regulate the gene encoding an immunodominant antigen expressed specifically in larval stage of Dirofilaria immitis.
批准号:
07670274
负责人:
SUGANE Kazuo
金额:
$1.41万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
1995
资助国家:
日本
项目状态:
已结题
起止时间:
1995 至 1996
中文摘要
我们对免疫双丝虫幼虫期特异性表达的免疫优势抗原编码基因Dg2和DgK进行了鉴定,并分析了该基因启动子区的功能。用秀丽隐杆线虫进行显微注射研究,DgK可能只在线虫的消化道中表达。
英文摘要
We characterized the genes (Dg2 and DgK) encoding an immunodominant antigen expressed specifically in larval stage of Dirofilaria immitis, and analyzed the function of promoter region of the gene. Microinjection study using Caenorhabditis elegans, the DgK might be expressed only in digestive tract of the nematode.
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依托单位: