Evaluation method of screening for the highly-sensitive subjects of airway allergy by using flow-volume pattern analysis (RAT-FEV1%diagram)

1995年对150名中年职工进行了肺功能和血清总IgE水平的检测。本文分析了16例非吸烟者和46例吸烟者的大鼠-FEV1%图与血清总IgE水平的关系。在IgE<100IU/ml组，大鼠-FEV1%图中A线的分布高于B线。本文对705名35岁以上男性中年职工的大鼠-FEV1%图与血清总IgE水平的关系进行了分析。在1997年的实验中，对1177名35岁以上的中年男性工人(非吸烟者442人，吸烟者735人)的资料进行了大鼠-FEV1%曲线(A-、B-、SA-、SB-线)与血清总IgE水平的关系分析，得出了与1997年相似的结果。在非吸烟者中，A系和SA系的分布均为63.3%和58.8%，而B系和SB系的分布分别为34.2%和34.5%。A系和SA系与B系和SB系的分布不同。(X2=28.21)。吸烟者中A线和SA线的分布均为48.5%和61.5%，而B线和SB线的分布分别为28.3%和25.7%，且血清总IgE<100IU/ml。A系和SA系与B系和SB系的分布不同。(X2=45.44)。此外，在IgE水平>100IU/ml组中，B线和Sb线的分布显著增加(71.4%和74.3%)。最后，大鼠-FEV1%图在呼吸道变态反应高敏人群的初筛方法中具有重要意义。

In 1995, one hundred and fifty middleaged workers were examined pulmonary function tests and total serum IgE level. The data of 16 nonnsmokers and 46 smokers of them were analyzed between the relation of RAT-FEV1% diagram and the level of total serum IgE.Distribution of A-line in RAT-FEV1% diagram were higher than those in B-line in the group of less than 100IU/ml of IgE.Distribution of B-line in the diagram were higher than those in A-line in the group of greater than 100 IU/ml of IgE.In the experiment of 1996, the data of 705 male middle-aged workers more than 35 years old were analyzed between the relation of RAT-FEV1% diagram and the level of total serum IgE.In the experiment of 1997, the data of 1177 male middleaged workers (442 nonsmokers and 735 smokers) more than 35 years old were analyzed between the relation of biological lines of RAT-FEV1% dia-gram (A-, B-, SA-, and SB-line) and the level of total serum IgE.Similar reults were obtained in the two experients.Thus, the results In 1997 were shown in this report. In nonsmokers, the distribution of A-line and SA-line were both 63.3% and 58.8%, but the distributions were 34.2% and 34.5% in B-, and SB-line, in the group, less than 100 IU/ml of total serum IgE level. The distribution was different among A- and SA-line on the one hand and B- and SB-line on the other . (x2=28.21). In smokers, the distributions of A-line and SA-line were both 48.5% and 61.5%, but the distributions were 28.3% and 25.7% in B-, and SB-line, in the group, less than 100 IU/ml of total serum IgE level. The distribution was different among A- and SA-line on the one hand and B-and SB-line on the other. (x2=45.44). Further, in the group of greater than 100 IU/ml of IgE level, the distribution showed a remarkable increase in B-and SB-line (71.4% and 74.3%). Finally, RAT-FEV1% diagram has a meaningful significance in the primary screening method for the highly-sennsitive group of airway allergy.