A Trial to Estimate the Action of Inhibitory System by Using Percutaneous Electrical Stimulation of Progressive Increasing intensity

临床上评价中枢神经系统对疼痛抑制作用的方法还没有得到很好的确立。因此，我们认为当受试者在第一次最强烈的刺激和最后一次刺激时识别出相同的强度感觉时，渐进增加的强度的测量(我们将增加的强度与第一次刺激的基本强度的比率称为下面的递增比率)作为对疼痛抑制作用的估计，我们试图测量健康成年人和疼痛患者的递增比率。方法：脉冲发生器设置为：脉冲6次，脉冲间隔2秒，占空比20%，输出电压2~10个，间隔5秒，每次重复递增电压3%或5%。刺激电极采用一次性针刺针和心电电极。结果：健康成人的递增比为11.9&lt；+-6.9(均值+-gt；SD)%，而疼痛患者疼痛皮损附近的递增比显著降低(0.3&lt；+-gt；0.9%)，疼痛缓解后恢复至健康成人水平(10.4&lt；+->6.5%)。痛期全身递增比下降，但痛灶远端明显高于痛区近端

The method with estimates the inhibitory action of CNS on pain clinically, has not been well established. So, we considered measurement of progressive increasing intensity when the person studied recognizes the same sensation of intensity at the first most strong stimulation and at the last stimulation (we call the ratio of increased intensity to first basal intensity of stimulation "progressive increasing ratio" below) as a estimation of inhibitory action on pain, and we tried to measure the progressive increasing ratio in healthy adults and the patients with pain. Methods : pulse generator was setted as below ; 6 pulses, 2 seconds pulse intervals, 20% of duty time, 2 to 10 voltage output, 5 seconds intervals, 3 or 5% progressive increasing voltage in every repetition. Disposable acupuncture needle and ECG electrode were used as stimulation electrodes. Results : the progressive increasing ratio was 11.9<plus-minus>6.9 (mean<plus-minus>SD) % in healthy adults, on the other hand, that was significantly decreased (0.3<plus-minus>0.9%) in the vicinity of painful lesion in the patient with pain, and that was recovered to the level of healthy adults (10.4<plus-minus>6.5%) after healing the pain. At painful stage, the decrease of the progressive increasing ratio was seen in whole body, but that of the distant site from painful lesion was significantly higher than that of the vicinity of painful