A foresight of appearance of maternity blues and a settlement of the care-systems

由于产后抑郁症的预防依赖于对这些体征的早期预测，因此我们认为，如果能够更早地进行预测，这将有助于建立支持系统。我们对40名孕妇在孕中期和产后第4天进行了纵向研究，旨在弄清孕期出现的心身症状与唾液中前列腺素D_2的关系，得到以下信息：1.产后忧郁症状的早期预测我们通过提问进行了测试。结果发现，妊娠中期出现心身症状“神经症症状重”组与产后第4天出现“产后焦虑感”组类似，证实了…期间出现心身症状。PgD_2值是评定PgD_2的客观指标。取唾液1ml，采用EIA法。结果发现，妊娠分娩妇女唾液中PGD_2含量高于非妊娠妇女。孕中期PGD_2值较高和产后第4天PGD_2值降低的两组产妇均有产后烦躁感。发现孕中期PGD_2评分较高者心身症状评分较高，产后第4天PGD_2值较低者心身症状评分较高，孕期唾液中PGD_2值在分娩后突然降低的激素环境变化可能是导致激惹和心身症状的原因之一。我们增加了PGD_2作为引起母性忧郁症状的因素之一，并进行了基础研究，以确保唾液中PGD_2测定的可靠性。较少

As prevention of maternity blues in a lying-in-period depends on how quickly foresee such signs, we believe if earlier prediction is possible, that will be useful in establishing the support system.We vertically studied 40 persons on mid-term of the pregnancy and at the fourth day in the lying-in-period aimed at clarifying relations between psychosomatic symptoms appeared in pregnancy and the value of PGD_2 in saliva and obtained the following information.1 Earlier prediction of maternity blues symptomsWe used 20 items of Zung's Self-Rating-Depression-Scale (SDS) and 24 items of MPI-Neurocism-Scale in rating maternity blues, and we tested through the question-nairing. We found that psychosomatic symptoms appeared in the group of women on mid-term of the pregnancy with "strong symptoms of neurosis" similarly appeared in the group of women at the fourth day in the lying-in period with "after childbirth feeling of irritations" and confirmed thus that psychosomatic symptoms appeared during … More pregnancy and also appeared after childbirth have a relationship.2 The value of PGD_2 is an objective indexIn rating PGD_2. we extracted 1ml of saliva and used EIA method. we found the value of PGD_2 in saliva of pregnant-childbed women showed higher than that in non-pregnant women. Both groups of women whose value of PGD_2 were higher on mid-term of the pregnancy and whose value of PGD_2 lowered at the fourth day of the lying-in-period have complained the after childbirth feeling of irritations.Concerning relations between the score of SDS and the value of PGD_2, we found the high score of psychosomatic symptoms in the group of women on mid-term of the pregnancy with higher score of PGD_2 and also in the group of women at the fourth day in the lying-in-period with lower value of PGD_2.Such hormone environmental changes as the value of PGD_2 in saliva in pregnancy suddenly lowers after childbirth could be causative of the feeling of irritations and psychosomatic symptoms. We add PGD_2 as one of the factors causing maternity blues symptoms and proceed our basic researches to ensure reliability in raing PGD_2 in saliva. Less