3T MR Imager for small animals

马丁路德大学哈勒·维滕贝格(MLU)申请采购一台场强为3特斯拉的临床前核磁共振设备。据计划，该装置将成为Halle MR成像核心设施(HMRICF)的一部分。主要用户将是来自药学研究所和医学院的研究小组。其中一个重点将是非侵入性磁共振成像，用于表征药物输送系统，特别是可生物降解的植入物和纳米级输送系统。核磁共振设备的另一个用途是为医学和药剂学中的几个研究小组成像药理学-肿瘤学问题。作为核心设施的一部分，核磁共振设备可供马丁·路德大学自然科学和医学领域的其他用户(第一优先)和非大学用户(第二优先)使用。核心机制HMRICF负责确定应用程序和技术支持的优先次序。预期用途的例子包括血管异常及其治疗的成像方法、心脏病问题的成像方法(心肌梗塞的临床前模型)、脂肪分布的测量、年龄相关变化的成像。计划加强和扩大自然科学学院不同工作组与医学工作组现有的合作。跨院系和跨学科合作的一个重点是开发创新的药物输送系统，供当地释放。例如，该设备将用于对豚鼠体内可生物降解的人工耳蜗进行成像。此外，该设备还将用于青年科学家的高级培训。计划将该设备用于医学物理研究过程中的学生教育，并规划硕士论文、毕业论文和博士学位论文，其中MRI的临床前成像将是必不可少的组成部分。

The Martin Luther University Halle Wittenberg (MLU) applies for the procurement of a preclinical MRI device with the field strength of 3 Tesla. It is planned that the device will become part of the Halle MR Imaging Core Facility (HMRICF). The primary users will be research groups from the Institute of Pharmacy and the School of Medicine. One focus of use will be non-invasive MR imaging for characterization of drug delivery systems, especially biodegradable implants and nanoscale delivery systems. Another focus for the use of the MRI device is for imaging pharmacological-oncological issues for several research groups in medicine and pharmacy. As part of the Core Facility, the MRI device is available to other Martin Luther University users from the natural sciences and medicine (first priority) as well as non-university users (second priority). The prioritization of the applications as well as the technical support is carried out by the Core Facility HMRICF. Examples of intended uses are imaging methods for vascular anomalies and their therapy, for cardiological questions (preclinical models of myocardial infarction), for the measurement of fat distributions, for the imaging of age-related changes. It is planned to intensify and expand existing co-operations of different working groups of the natural science faculties with working groups of medicine. One focus of the interfaculty and interdisciplinary cooperation is the development of innovative drug delivery systems for local release. For example, the device will be used for imaging of biodegradable cochlear implants in guinea pigs. Furthermore, the device will be used for advanced training of young scientists. It is planned to use the device for the education of students in the course of studies of medical physics, furthermore master theses, diploma theses and doctorates are planned, in which preclinical imaging by MRI will be an essential part.