The study of the infection route of periodontopathic bacteria to implants and the time of infection.

本研究旨在明确牙周致病菌对种植体的感染途径和感染时间。在解释了本研究的概要后，获得了6名完成牙周治疗并计划植入种植体的患者的知情同意书。对剩余牙齿进行牙周检查（PII、PD、GI）、细菌采样和采血。术后2周、1、3、6个月、1年分别对种植体周围组织进行牙周检查和细菌学检查。1年后，再次对剩余牙齿进行牙周检查、细菌采样和血液采集。在TSHM培养基和TSBV培养基中进行厌氧培养，测定细菌总数，并检查黑色厌氧杆菌（BPAR）和伴放线放线杆菌（A. a）。从血液中分离血清 ...更多信息 并测定牙周致病菌抗体滴度。在每个患者中，剩余牙齿的牙周检查、细菌检查或ELISA显示，与术前状态相比，种植体插入1年后口腔卫生没有变化，种植体的牙周检查表明种植体插入过程良好。植入物的细菌检查显示，直到术后1个月，细菌总数较高，在此期间检查的13个部位中，有3个部位存在BPAR。在13个部位中有7个检测到A. a，检测时间从术后2周至1年不等。在种植体中显示这些牙周病细菌的患者中，这些细菌也在剩余的牙齿中检测到。这些结果表明，种植体周围的组织感染，口腔细菌或BPAR发生种植体插入后相对较早，和牙周病细菌在剩余的牙齿与种植体感染。少

This study was carried out to clarify of the infection route of periodontopathic bacteria to implants and the time of infection. After explanation of the outline of this study, informed consent was obtained from 6 patients in whom periodontal treatments was completed, and implant insertion was planned. Periodontal examination (PII, PD, GI) of the remaining teeth, sampling of bacteria, and blood collection were performed. A total of 13 implants were inserted, and periodontal examination of the tissue around the implant and sampling of bacteria were performed 2 weeks, 1,3,6, months, and 1 year after operation. After 1 year, periodontal examination of the remaining teeth, sampling of bacteria, and blood collection were performed again. The bacteria were anaerobically cultured in TSHM medium and TSBV medium, and the total bacteria count was determined, and black pigmented anaerobic rods (BPAR) and Actinobacillus actinomycetemcomitans (A.a) were examined. Serum was separated from the blood … More samples, and the antibody titer against periodontopathic bacteria was determined. In each patient, periodontal examination of the remaining teeth, bacterial examination, or ELISA reveald no changes in oral hygiene 1 year after implant insertion compared with the preoperative state, and periodontal examination of the implant indicated a good course of implant insertion. Bacterial examination of the implant showed a high total bacteria count until 1 month after operation and presence of BPAR at 3 sites of 13 sites examined during this period. A.a was detected at 7 of the 13 sites, and the time of detection varied from 2 weeks to 1 year after operation. In patients showing these periodontopathic bacteria in the implant, these bacteria were also detected in the remaining teeth. These results suggested that infection of the tissue around the implant, with oral bacteria or BPAR occurs relatively early after implant insertion, and periodontopathic bacteria in remaining teeth are associated with implant infection. Less