Host Selection of Anti-tumor Basidiomycetes meshimakobu (Phellinus linteus) for yamaguwa (Morus bombycis).

山口木被认为是日本最耐用的木材之一。抗肿瘤的蘑菇，是山形木中常见的一种。我们试图弄清楚mesimakobu选择山竹作为寄主木材的原因。山川木对山川菌的菌丝生长的促进作用大于山竹木和科那拉木。甘露茸、川茸和香菇在山川林中的生长受到抑制。山楂热水提取物对木腐菌有促进作用，甲醇提取物对其他木材腐菌有抑制作用。山茱萸甲醇提取物的酚组分对木材腐烂真菌的抑菌活性较强，对木材腐烂真菌的抑菌活性较弱。推测氧化白藜芦醇是山楂甲醇提取物中苯酚组分的主要抗真菌因子。然而，即使在培养基中添加了氧化白藜芦醇，Meshimakobu也非常弱，很容易被其他木材腐烂真菌打败。从这些结果来看，由于抗真菌因子氧化白藜芦醇对其他强腐木真菌的生长有明显的抑制作用，因此只有山口木才能勉强存活。

Yamaguwa is well known as one of the most durable wood for decay in Japan. Anti-tumor mushroom, meshimakobu is found typically in this yamaguwa wood. We attempted to clear the reason why mesimakobu selects yamaguwa as a host wood.The mycerial growth of mesimakobu in yamaguwa wood was promoted more than kunugi and konara wood. In the case of mannentake, kawaratake and shiitake, their growth were depressed in yamaguwa wood. It was found that a hot water extracts of yamaguwa contained a promoter for meshimakobu and methanol extracts contained inhibitors for other wood rotting fungi.The phenol fraction of methanol extracts of yamaguwa showed greater antifungal activities for wood rotting fungi, other than meshimakobu. Oxyresveratrol was presumed as a main antifungal factor in a phenol fraction of methanol extracts of yamaguwa. Meshimakobu was however very weak and easily defeated by other wood rotting fungi even when oxyresveratrol was added in a culture medium.From these results, it seems that meshimakobu could be barely survived only in yamaguwa because antifungal factor, oxyresveratrol prevented significantly the growth of other strong wood rotting fungi.