Hemodynamic effects on the treatment of cerebral aneurysms evaluated using hydraulic vascular model
Hemodynamic effects on the treatment of cerebral aneurysms evaluated using hydraulic vascular model
批准号:
10671331
负责人:
NAGASAWA Shiro
金额:
$0.38万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
1998
资助国家:
日本
项目状态:
已结题
起止时间:
1998 至 1999
中文摘要
1、用于基底关节炎的父闭合疗法;使用一种液压模型,模型关节炎的半寿命被测量为一种内部停滞指数的方法。两个posterior communicating arteries (PCom)的比例被定义为diameter ratio (DR)。阻塞治疗在4个不同的站点中模拟,阻塞治疗明显增加了对阻塞站点的半生命依赖和DR值的最大值在A型和D型中无限大值的最大值25秒。旁路减少了切线流动体积到非线性颈部的位置,并在A型和B型中增加了时间标记,显然在C型中,略微在D型中,父母电池封闭疗法对患者的径向比率低于0.70。Additional bypass placement to the occlusion therapy is very useful in enhancing the aneurysmal stagnation. 2, Characteristics of curvature aneurysms at paraclinoid area。Hemodynamics of paraclinoid aneurysms were investigated focusing on the effects of their locations and shape of the carotid siphon。Carotid Siphon的透明硅模型是构造的。当虹吸角为0 °时,半生命价值在C2-C3交叉点温度中是最低的,在C2分段温度中是最高的。当C2-C3交叉点内链保持低值不受控制的角度,C3段内链值被分解,C2段内链值随着增加而增加。这些半生命的变化是因为在哪个更快的移动流体组件撞击了曲线墙的变化,这些结果被认为是有用的,以确定手术指标、治疗模式和手术后管理的结果。
英文摘要
1, Parent occlusion therapy for basilar head aneurysm.Using a hydraulic model, half-life of the dye in the model aneurysm was measured as an index of the intraaneurysmal stagnation. The ratio of diameters of the two posterior communicating arteries (PCom) is defined as diameter ratio (DR). Occlusion therapy was simulated in 4 different sites.Occlusion therapy significantly increased the half-life depending on the occlusion site and DR values with the maximum values of infinite in Type A and 25 sec in Type D. placement of the bypass decreased the tangential flow volume to the aneurysmal neck, and increased the time markedly in Types A and B, considerably in Type C and slightly in Type D.Parent artery occlusion therapy has been considered less beneficial for the patients with the diameter ratio less than 0.70. Additional bypass placement to the occlusion therapy is very useful in enhancing the aneurysmal stagnation.2, Characteristics of curvature aneurysms at paraclinoid area.Hemodynamics of paraclinoid aneurysms were investigated focusing on the effects of their locations and shape of the carotid siphon. Transparent silicon model of the carotid siphon was constructed. When the siphon angle was 0゜, the half-life value was the lowest in the C2-C3 junction aneurysm, highest in the C3 segment aneurysm and intermediate in the C2 segment aneurysm. While the C2-C3 junction aneurysm maintained low values regardless of the angle, the C3 segment aneurysm values decreased and C2 segment aneurysm values increased with increases in the angle. These changes of half-life occur because the point at which the faster moving fluid component strikes the curved wall changes according to the siphon angle.These results are considered useful to determine the surgical indications, treatment modalities and postsurgical management of the aneurysms.
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Nagasawa S, Kawabata S, Kawanishi M: "Cortical arterial flow volumes in posterior circulation measured by intraoperative Doppler sonography"J Cereb Blood Flow Metab. 19. S581 (1999)
Nagasawa S、Kawabata S、Kawanishi M:“通过术中多普勒超声检查测量后循环皮质动脉流量”J Cereb Blood Flow Metab。
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Shiro Nagasawa: "Simulation of therapeutic parent artery occlusion for basilar aneurysm"Neurological Research. 21. 180-184 (1999)
长泽史郎:“基底动脉瘤治疗载瘤动脉闭塞的模拟”神经学研究。
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長澤 史朗: "脳底動脈巨大動脈瘤に対する親動脈閉塞術のモデル解析"Neurological Surgery(脳外). 27. 723-728 (1999)
Shiro Nagasawa:“巨大基底动脉瘤的载瘤动脉闭塞模型分析”《神经外科》27. 723-728 (1999)。
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Shiro Nagasawa: "Hemodyaamic simulation study of cevebral aeteriouenous malformation" Journal of Cevebral Flew and Metabolism. 16. 162-169 (1996)
Shiro Nagasawa:“脑血管畸形的血液模拟研究”《脑血管与代谢杂志》。
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Nagasawa S, Sakaguchi I, Ohta T: "The posterior temporal artery as the recipient in superficial temporal artery to posterior cerebral artery bypass. Technical note."Surg Neurol. 52. 73-77 (1999)
Nagasawa S、Sakaguchi I、Ohta T:“颞后动脉作为颞浅动脉至大脑后动脉旁路的受体。技术说明。”Surg Neurol。
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