Vo_2 Kinetics during heavy exercise.

近年来，运动时的肺氧摄取（Vo 2）动力学作为评价有氧工作能力的新标准受到了广泛的研究，因为非稳态是生物体中更常见的状态。通过对运动的稳态和非稳态Vo 2反应的严格分析，我们能够更深入地了解代谢控制和有氧工作能力的基本机制，这些机制决定了我们在日常生活中对运动的适应性。至关重要的是澄清休息-运动过渡期间的Vo 2响应的精确特征以及O2输送和/或利用是否是运动开始后Vo 2响应的速率限制因素。我们总结了最近对上述问题的研究，特别是旨在系统地改变（增加/减少）氧气输送和/或利用的调查结果，并确定这种扰动对中度运动（运动结束时Vo 2低于乳酸阈值（LT））和重度运动（高于LT）的Vo 2动力学反应的影响。

In recent years, pulmonary oxygen uptake (Vo2) kinetics during exercise have been investigated intensely as a new criterion for the evaluation of aerobic work capacity, since a non-steady state is the more usual condition in organisms. From rigorous analysis of both steady- and non-steady state Vo2 responses to exercise, we are able to gain a deeper insight into the fundamental mechanisms of metabolic control and aerobic work capacity, which determine our adaptability to exercise in daily life. It is of critical importance to clarify both the precise features of the Vo2 response across the rest- exercise transition and whether 02 delivery and/or utilization is the rate-limiting factor in Vo2 response following the onset of exercise. We summarized recent studies on the above issues and, in particular, the results of investigations designed to alter (increase/decrease) oxygen delivery and/or utilization systematically and to determine the effect of such perturbations on the kinetic response of Vo2 to moderate exercise (where end-exercise Vo2 is below the lactate threshold (LT)) and heavy exercise (where it is above LT).