Establishment of non-invasive examination of swallowing patterns and changes in electrogastrogram during normal swwallowing.

本研究旨在建立正常吞咽模式的非侵入性检查，并阐明正常吞咽过程中胃动力的变化。研究结果如下：(1)为了考察正常的吞咽模式，我们调查了自发性吞咽时的喉部运动、与吞咽有关的声音和鼻腔温度。此外，在正常成人中，研究了颈椎位置和团体量对这些参数的影响。一盏红灯亮起，就触发了自愿吞咽。吞咽20cc水的受试者与10cc水的受试者相比，咽喉运动和吞咽呼吸暂停的持续时间显著延长。与前屈20°相比，背屈10°时，喉运动潜伏期和吞咽呼吸暂停潜伏期明显缩短，喉运动持续时间明显延长。从这些发现可以看出，健康的受试者保持在喉和腭部的抬高位置m…更多的奥利，以防止因大容量的团剂而误服。水在背屈时迅速流入喉部。因此，这进一步表明，受试者在背屈状态下吞咽时，喉和腭磨牙运动的起始时间缩短，喉头抬高延长。(2)为了阐明与正常吞咽相关的胃动力变化，记录了不同溶液引起的自愿吞咽和吞咽反射过程中的胃电(EGG)。当受试者吞下20cc的水时，食道扩张可使胃电的波幅一过性增加。咽内注射0.05%柠檬酸、水和0.9%氯化钠可引起一过性胃电幅度增加。胃电幅值按柠檬酸-水-氯化钠的顺序递增。吞咽反射潜伏期也由大到小依次为柠檬酸、水和氯化钠。这些结果提示，机械刺激和化学刺激对咽喉部的胃运动有影响。较少

This study was conducted to establish non-invasive examination of normal swallowing patterns, and to clarify gastric motility changes during normal swallowing. The results were as follows :(1) To examine normal patterns of swallowing, we investigated laryngeal movement, sound associated with swallowing and temperature of nasal cavity during voluntary swallowing. Furthermore, effects of cervical position and bolus volume on these parameters were investigated in normal adults. Voluntary swallowing was triggered by onset of a red lamp. Duration of laryngeal movement and deglutition apnea were significantly elongated when subjects swallowed 20cc water compared with 10cc water. In 10 degree dorsiflexion, latencies of laryngeal movement and deglutition apnea were significantly shortened and duration of laryngeal movement was elongated compared with those in 20 degree anteflexion. From these findings, it was suggested that healthy subjects retained at elevated position of larynx and palatum m … More olle to prevent misswallowing due to large volume of bolus. Water rapidly flowed into larynx in dorsiflexion. Thus, it was further suggested that subjects shortened onset of larynx and palatum molle movement and elongated laryngeal elevation when they swallowed in dorsiflexion.(2) To clarify changes in gastric motility associated with normal swallowing, elctrogastrogram (EGG) was recorded during voluntary swallowing and swallowing reflex elicited by injection of various solution. Amplitude of EGG was transiently increased by dilation of esophagus when subjects swallowed 20cc water. Injection of 0.05% citric acid, water and 0.9% NaCl into pharynx induced transient increase of amplitude of EGG. The amplitude of EGG increased in the order of citric acid > water > NaCl. The latency of swallowing reflex was also shortened in the order of citric acid > water > NaCl. From these findings, it was suggested that gastric motility is influenced by mechanical and chemical stimulation to pharyngeal and laryngeal region. Less