The establishment of functional-morphological and respiration-physiologic diagnosis of the upper respiratory tract failure in the postoperative
The establishment of functional-morphological and respiration-physiologic diagnosis of the upper respiratory tract failure in the postoperative
批准号:
13672083
负责人:
SOMEYA Genji
金额:
$2.3万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2001
资助国家:
日本
项目状态:
已结题
起止时间:
2001 至 2003
中文摘要
由于手术部位主要在颌部口腔,术后上呼吸道狭窄和阻塞的发生率很高。此外,肌肉松弛剂和麻醉剂的作用在从全身麻醉剂唤醒后立即保持,并且容易出现低回忆状况的呼吸抑制的情况。尽管在临床上十分重要,但对其产生原因及发生机制的探讨,术前CT侧位头颅影像对比分析发现不完整。此外,目前不明确的点也很多.本研究通过超声成像设备、呼吸相关肌肌电图和通气生理检测方法,调整X线电视和功能形态分析方法,对阻塞性呼吸障碍的病情进行综合分析和诊断,包括上呼吸道、下呼吸道、上呼吸道、下 ...更多信息 术后呼吸道衰竭发生率呈动态变化。此外,还阐明了原因和发生机制。本研究期间阐明了以下内容:1.关于低浓度全身麻醉药以三叉神经为介质对反射系统的影响,检查了氯胺酮、咪达唑仑对反射系统之一的外感受性抑制(ES1和ES2)的影响,外感受性抑制是比例控制系统下降以三叉神经为介质的全身麻醉药(低浓度)。氯胺酮、咪达唑仑不能识别三叉神经对反射系统的影响。同时,证明了比例控制系统下降影响上位中枢水平的反射系统,尽管这种影响不是由脑干区的三叉神经反射系统引起的。本研究结果显示,全身麻醉药对上呼吸道功能的影响主要是对颌口腔功能的影响。2.全身麻醉药对吞咽功能的影响。全麻术后苏醒后常出现呼吸功能下降。吞咽反射与呼吸运动的关系是深层次的。研究结果表明,呼吸功能下降与误吸诱导有关。本实验采用呼吸抑制法,对家兔生理性呼吸肌运动进行抑制。结果表明,气道压力降低,从咽部到食道的压力梯度减小。少
英文摘要
The frequency of upper respiratory tract stenosis and blockade in the postoperative is very high for the fact of the operation mainly on the jaw oral cavity in which it comes-out. In addition, the action of muscle relaxant and anesthetic remains right after the arousal from the general anesthetic agent, and it becomes liable a case in which there is the respiratory depression for the low recall condition. In spite of being clinically very important, the investigation of the cause of generation and occurrence mechanism is found preoperation CT side cephalo photograph comparison analysis fragmental. In addition, at present unclear point is also abounding. This study adjusted roentgen television and functional-morphological analysis method by the ultrasound imaging equipment and electromyogram of the respiration relation muscle and ventilation physiological testing method, it comprehensively analyzed and diagnosed the disease state of obstructive respiration disorder including the upper r … More espiratory tract failure in the postoperative which dynamically changed. In addition, it has been made that the cause and occurrence mechanism are clarified to be a purpose. The following was clarified in this study period.1.On the effect on reflex systems in which the general anesthetic agent of low concentration uses trigeminal nerve as medium.Ketamine, midazolam, effect on Exteroceptive Suppression(ES1 and ES2) which is one of the reflex system jaw opening reflex in which the proportional control system fall uses trigeminal nerve as medium of general anesthetic agent(low concentration) were examined. Ketamine, midazolam did not recognize the effect of the trigeminal nerve on reflex systems. In the meantime, it was proven that the proportional control system fall affected reflex systems at the epistasis center level, though the effect is not caused trigeminal nerve reflex systems in the brain stem division. The general anesthetic agent is upper respiratory tract failure mainly on jaw oral cavity function on this study result.2.The effect of the decreased respiratory function by general anesthetic agent on the swallow function. There is often a decreased respiratory function fight after the general anesthesia arousal in the postoperative. The relation between deglutition reflex and respiratory movement is deep. It was indicated that the decreased respiratory function was connected with the induction of the aspiration from this study result. In this study the movement of physiological respiratory muscle was suppressed from experimental model using the rabbit by respiratory depression. It was proven the lowering of airway pressure and pressure gradient from the pharynx to the gullet decreased. Less
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会议论文
Construction of a Support System for Regional Home Dental Care using Computer Network
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批准号:11794024
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项目类别:Grant-in-Aid for University and Society Collaboration
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资助金额:$0.0万
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财政年份:1999
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负责人:SOMEYA Genji
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依托单位:
The physiological and behavioral evaluation of patient-control sedation
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批准号:07672162
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.41万
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财政年份:1995
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负责人:SOMEYA Genji
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依托单位:
Changes in nasal resistance and air way structure associated with orthognathic surgery.
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批准号:05671663
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.41万
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财政年份:1993
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负责人:SOMEYA Genji
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依托单位:
海外基金