Relationship between the plasma concentration of sulfoconjugated catecholamines and physical training and blood pressure

本研究的目的是确定耐力运动训练是否会改变人血浆中共轭儿茶酚胺的浓度。为此，我们进行了两个实验：1)训练实验（3个月的训练和6个月的去训练）和2)对比实验。在训练实验中，14名男性受试者被分为耐力训练组（N=7）和久坐组（N=7）。训练组在3个月内，每周3 - 5天，每天跑步或骑车30毫米以上，然后停止训练6个月。在训练期间和训练结束6个月后，每组每个月进行一次血液采样和血压测量。对比实验采用高效液相色谱法对16名男性大学跑步运动员、10名男性柔道运动员和12名未经训练的男性受试者进行血浆游离儿茶酚胺和磺化儿茶酚胺（肾上腺素、去甲肾上腺素和多巴胺）分析。训练组经过12周的训练期后，虽然体脂率明显下降，最大摄氧量明显增加，但血浆游离儿茶酚胺和结合儿茶酚胺的浓度没有明显变化。在训练和去训练期间，血浆游离儿茶酚胺和磺化儿茶酚胺的浓度也没有显著差异。此外，所有血浆游离儿茶酚胺和共轭儿茶酚胺在耐力跑者、柔道运动员和未训练组之间没有差异。因此，我们得出结论，血浆中磺化儿茶酚胺不会因运动训练而改变，至少在男性中是这样。

The purpose of the present study was to determine whether endurance-exercise training alters the concentrations of plasma conjugated catecholamines in man. To investigate this, we conducted two experiments : 1)a training experiments (3-month training and 6-month (detraining) and 2)a comparison experiment. In the training experiment, 14 male subjects were divided into endurance training group (N=7) or sedentary group (N=7). Training group exercised running or cycling exercise for 30 mm or more a day, 3 to 5 days a week during 3 months, and then they stopped the training for 6 months. In each group, blood sampling, measurements of blood pressure were conducted every month during training and after 6 months detraining. In the comparison experiment, 16 male university runners, 10 male Judoist and 12 untrained male subjects participated in this -study Plasma free and sulfoconjugated catecholamines (adrenaline, noraclrenaline and dopamine) were analyzed by high-performance liquid chromatography.In training group after the 12-wk training period, although there was significant decrease in Percentage of body fat and was significant increase in maximal oxygen uptake, concentration of plasma free and conjugated catecholamines did not show any changes significantly. No significant difference in all concentrations of plasma free and sulfoconjugated catecholamines was also found between the training and the detraining period. Furthermore, there were no differences in all plasma free and conjugated catecholamines among the endurance runner, Judoist, untrained group. Therefore, we concluded that plasma sulfoconjugated catecholamines do not change as a result of exercise training, at least in man.