Development of Semiconductor PET Scanner with the Ultra High Resolutionof less than 1mm FWHM : Next Generation PET

癌症的死亡率每年都在增加，因此需要能够检测微小癌症的高分辨率pet。我们通过小型化碲化镉半导体探测器开发了空间分辨率小于1mm的半导体PET，而使用闪烁探测器的传统PET只能获得约4mm的分辨率。它激发了超高分辨率PET时代的曙光。通过对小鼠的PET实验，我们在世界上首次展示了1mm肿瘤的FDG图像。此外，我们成功地开发了二维位置敏感碲化镉探测器，提供了高分辨率和高灵敏度。我们将这些探测器堆叠在一起，制造出三维位置敏感探测器块，并开发出超高分辨率的人类用半导体PET。

The mortality rate for cancer is increasing every year and high resolution PETs which can detect minute cancer are called for now. We developed a semiconductor PET with a spatial resolution of less than 1mm by miniaturizing CdTe semiconductor detectors, while only about 4mm resolution is obtained in the conventional PET using scintillation detectors. It inspires the dawn of super-high resolution PET age. By a mouse experiment with the PET, we could show an FDG picture of 1mm cancers for the first time in the world. Furthermore, we succeeded to develop two-dimensional position sensitive CdTe detectors which provide both high resolution and high sensitivity. Stacking these detectors, we manufactured three-dimensional position sensitive detector blocks and developed a super-high resolution semiconductor PET for humans.