Influence of abnormal body temperature on expression of mucin in the respiratory tract under the artificial respiration Hyperthermia vs hypothermia-
Influence of abnormal body temperature on expression of mucin in the respiratory tract under the artificial respiration Hyperthermia vs hypothermia-
批准号:
19791072
负责人:
HASEGAWA Akira
金额:
$2.38万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2009
中文摘要
炎症使呼吸道黏液蛋白增加,但不清楚黏液蛋白的表达是否受到体温异常的怎样的影响。首先,我澄清了炎症和体温的关系。已知热休克蛋白(HSP)对侵袭具有细胞保护作用。制作大鼠内毒素休克模型,观察诱导热休克后的保护作用。结果表明,添加热应激(42℃15min)诱导热休克,可明显抑制炎症反应,提高成活率。今后我将进一步推进体温及其与粘蛋白表达关系的研究。
英文摘要
Inflammation lets mucin in the respiratory duct increase,but does not understand whether expression of mucin comes under what kind of influence by abnormal body temperature. First of all, I clarified relations of inflammation and body temperature. It is known that we have cytoprotective protection effect for aggression in heat shock protein (HSP). I made a rat endotoxin shock model and examined protection effect when I induced HSP. As s result, it was recognized that HSP was induced by adding heat stress (42℃15minutes), and inhibited inflammation significantly, and improved the survival rate. I will push forward study about body temperature and relations with expression of mucin more in future.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
敗血症の致死的メディエーターであるHMGB1に対するHSPの効果
HSP 对败血症致命介质 HMGB1 的影响
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[長谷川輝, 岩坂日出男, 萩原聡, 野口隆之, 長谷川輝, 長谷川輝]
通讯作者:
長谷川輝
DOI:
10.1016/j.jss.2009.10.015
发表时间:
2011-07-01
期刊:
JOURNAL OF SURGICAL RESEARCH
影响因子:
2.2
作者:
[Hasegawa, Akira, Iwasaka, Hideo, Noguchi, Takayuki]
通讯作者:
Noguchi, Takayuki
Study on mechanism of grain boundary embrittlement of austenitic stainless steel after irradiation using in-situ monitoring system of grain boundary separation
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批准号:24656563
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.58万
-
财政年份:2012
-
负责人:HASEGAWA Akira
-
依托单位:
Creation of super high performance photocatalyst by control of nanomicrostructure of titanium oxide
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批准号:18550183
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.62万
-
财政年份:2006
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负责人:HASEGAWA Akira
-
依托单位:
Improvement of Validation Technique for Long Term Soundness of In-core Component Materials of Light Water Reactor Plant after Repair and Maintenance
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批准号:17360451
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$10.43万
-
财政年份:2005
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负责人:HASEGAWA Akira
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依托单位:
Mapping of asperities and estimation of spatiotemporal distribution of interplate slip
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批准号:15204037
-
项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$26.21万
-
财政年份:2003
-
负责人:HASEGAWA Akira
-
依托单位:
Development of maintenance technique for materials of core components in light-water reactor using ion-beam irradiation
-
批准号:14380230
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.28万
-
财政年份:2002
-
负责人:HASEGAWA Akira
-
依托单位:
Study on stresss concentration mechanism on active faults
-
批准号:11440128
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$5.76万
-
财政年份:1999
-
负责人:HASEGAWA Akira
-
依托单位:
Study on Seismic Design of Bridges Systems
-
批准号:11695057
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$2.5万
-
财政年份:1999
-
负责人:HASEGAWA Akira
-
依托单位:
Relativistic current- and spin-density functional theory and its application to f-electron systems
-
批准号:09640424
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.86万
-
财政年份:1997
-
负责人:HASEGAWA Akira
-
依托单位:
Comparative study on crustal earthquakes along active faults
-
批准号:08041093
-
项目类别:Grant-in-Aid for international Scientific Research
-
资助金额:$2.82万
-
财政年份:1996
-
负责人:HASEGAWA Akira
-
依托单位:
Optical soliton communication-Application to the long distance and high data-bit communication-
-
批准号:07044146
-
项目类别:Grant-in-Aid for international Scientific Research
-
资助金额:$4.86万
-
财政年份:1995
-
负责人:HASEGAWA Akira
-
依托单位:
Imaging of Mantle Diapir by Seismic Waves
-
批准号:07454098
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$4.54万
-
财政年份:1995
-
负责人:HASEGAWA Akira
-
依托单位:
Aging Problems of the Mentally Handicrpped
-
批准号:06451043
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$4.03万
-
财政年份:1994
-
负责人:HASEGAWA Akira
-
依托单位:
Fermi Surfaces of Magnetic Uranium Compounds
-
批准号:06640471
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.34万
-
财政年份:1994
-
负责人:HASEGAWA Akira
-
依托单位:
Study on crustal earthquakes along cinvergent plate boundary
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批准号:05041050
-
项目类别:Grant-in-Aid for international Scientific Research
-
资助金额:$3.2万
-
财政年份:1993
-
负责人:HASEGAWA Akira
-
依托单位:
A study of deep structure of volcanoes and crustal earthquakes by seismic observations
-
批准号:04452061
-
项目类别:Grant-in-Aid for General Scientific Research (B)
-
资助金额:$3.33万
-
财政年份:1992
-
负责人:HASEGAWA Akira
-
依托单位:
Reserch on behavior of optical soliton and their application to ultra long distance, ultra high speed communications.
-
批准号:04102003
-
项目类别:Grant-in-Aid for Specially Promoted Research
-
资助金额:$118.4万
-
财政年份:1992
-
负责人:HASEGAWA Akira
-
依托单位:
Chemical synthesis of animal cell-surface glycoconjugates and analysis of the biological functions
-
批准号:03660132
-
项目类别:Grant-in-Aid for General Scientific Research (C)
-
资助金额:$1.28万
-
财政年份:1991
-
负责人:HASEGAWA Akira
-
依托单位:
Electronic states and the Fermi surface in f-electron compounds
-
批准号:03640303
-
项目类别:Grant-in-Aid for General Scientific Research (C)
-
资助金额:$1.15万
-
财政年份:1991
-
负责人:HASEGAWA Akira
-
依托单位:
Synthesis and function analysis of Gangliosides
-
批准号:63560122
-
项目类别:Grant-in-Aid for General Scientific Research (C)
-
资助金额:$1.41万
-
财政年份:1988
-
负责人:HASEGAWA Akira
-
依托单位:
Clinical and basical research for blood group ABO-incompatible kidney transplantation.
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批准号:62480342
-
项目类别:Grant-in-Aid for General Scientific Research (B)
-
资助金额:$4.35万
-
财政年份:1987
-
负责人:HASEGAWA Akira
-
依托单位:
国内基金
海外基金
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