Control of nonlinear processes of protein solution and biological cells induced by focused femtosecond laser
Control of nonlinear processes of protein solution and biological cells induced by focused femtosecond laser
批准号:
19686007
负责人:
HOSOKAWA Youchiroh
金额:
$16.47万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (A)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2010
中文摘要
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英文摘要
When an intense infrared-femtosecond-laser is focused into biological materials, shockwave and cavitation bubble are generated at the laser focal point, in which an explosive morphological change of water is induced by an effective multiphoton absorption. I developed a new local force measurement system to estimate the impulsive force due to the shockwave and cavitation bubble generated in biological materials and elucidated time and spatial evolution of these phenomena. On the basis of this knowledge, new control and measurement methods of single cell or intracellular protein were devised.
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DOI:
10.1073/pnas.1006847108
发表时间:
2011-02-01
期刊:
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
影响因子:
11.1
作者:
[Hosokawa, Yoichiroh, Hagiyama, Man, Ito, Akihiko]
通讯作者:
Ito, Akihiko
Induction of the cell-cell connections by using in-situ laser lithography on a perfluoroalkyl-layered cultivation platform.
在全氟烷基分层培养平台上使用原位激光光刻诱导细胞间连接。
DOI:
--
发表时间:
2011
期刊:
Chem Bio Chem Vol.12
影响因子:
--
作者:
[K.Okano, D.Yu, A.Matsui, Y.Maezawa, Y.Hosokawa, A.Kira, M.Matsubara, I.Liau, H.Tsubokawa, H.Masuhara.]
通讯作者:
H.Masuhara.
フェムト秒レーザーによる個別細胞パターニングプロセス
使用飞秒激光的单个细胞图案化工艺
DOI:
--
发表时间:
2007
期刊:
影响因子:
--
作者:
[細川 陽一郎, 宇和田 貴之, 瀧澤 典子, 岡野 和宣, 増原 宏]
通讯作者:
増原 宏
Nanoparticles injection into single animal cells by femtosecond laser-induced impulsive force
通过飞秒激光诱导脉冲力将纳米粒子注射到单个动物细胞中
DOI:
--
发表时间:
2007
期刊:
影响因子:
--
作者:
[A.Yamaguchi, Y.Hosokawa, G.Louit, T.Asahi, H.Masuhara, C.Shukunami, Y.Hiraki.]
通讯作者:
Y.Hiraki.
Cell Viability after Femtosecond Laser Ablation of Tissue
飞秒激光组织消融后的细胞活力
DOI:
--
发表时间:
2007
期刊:
影响因子:
--
作者:
[Yoichiroh Hosokawa, Noriko Takizawa, Takayuki Uwada, Kazunori Okano, Hiroshi Masuhara]
通讯作者:
Hiroshi Masuhara
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