Exercise therapy and immune function in patients with chronic respiratory failure

目的是确定运动训练对慢性呼吸道疾病患者唾液和呼气凝析液（EBC）免疫功能变化的影响。唾液和血清分泌免疫球蛋白A （SIgA）作为免疫功能的指标。在EBC标本中无法测量呼吸道SIgA的产生，因此EBC标本不能用于监测SIgA浓度。以医院为基础的肺部康复计划设计了运动训练和呼吸再训练，并没有降低唾液中抗氧化剂的SIgA和免疫力。本研究结果表明，肺部康复可能有助于提高免疫功能，也有助于改善身体状况和运动表现。

The objective was to determine the effects of exercise training on changes in salivary and exhaled breath condensate (EBC) immune function in patients with chronic respiratory disease. As an indicator of an immune functions, secretary immunoglobulin A (SIgA) in saliva and EBC was measured. Airway production of SIgA was unable to be measured in EBC specimens and, therefore, EBC specimens cannot be used to monitor SIgA concentration. Hospital-based pulmonary rehabilitation program which designed exercise training and breathing retraining, did not decrease SIgA and immunity with antioxidants in saliva. The result of this study suggests that pulmonary rehabilitation could be a useful for improving immune function, also makes improving physical conditioning and exercise performance.