Prognosis assesment by quantitative RT-PCR analysis of chimeric Iμ/BCL6 tanscripts
Prognosis assesment by quantitative RT-PCR analysis of chimeric Iμ/BCL6 tanscripts
批准号:
20791233
负责人:
LEE Koutetsu
金额:
$2.16万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2009
中文摘要
嵌合Ig-BCL 6转录本在正常人扁桃体和脾细胞中发现。IG/BCL 6染色体易位的出现与表达生殖中心B细胞的细胞有关。提示恶性淋巴瘤组织中IG/BCL 6转录本的表达水平较高。
英文摘要
The chimeric Ig-BCL6 transcripts found in normal human tonsil and spleen cells. The appearance of Ig/BCL6 chromosomal translocations was associated with the cells expressing germinal center B cell. This study showed higher grade of malignant lymphoma express much quantity of Ig/BCL6 transcripts.
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